Item no. |
ELS-PKSH032670-10ug |
Manufacturer |
Elabscience
|
Amount |
10ug |
Category |
|
Type |
Proteins |
Specific against |
Human |
Host |
E.coli |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Alias |
Importin Subunit Alpha-2, Karyopherin Subunit Alpha-2, RAG Cohort Protein 1, SRP1-Alpha, KPNA2, RCH1, SRP1 |
Similar products |
KPNA2, SRP1, RCH1, Importin Subunit Alpha-2, Karyopherin Subunit Alpha-2, RAG Cohort Protein 1, SRP1-Alpha |
Available |
|
Synonym |
Importin Subunit Alpha-2, Karyopherin Subunit Alpha-2, RAG Cohort Protein 1, SRP1-Alpha, KPNA2, RCH1, SRP1 |
Storage |
< -20CC |
Protein Construction |
Recombinant Human Karyopherin Subunit alpha-2 is produced by our E.coli expression system and the target gene encoding Met1-Phe529 is expressed with a 6His tag at the N-terminus. |
Sequence |
Met 1-Phe529 |
Fusion tag |
N-6His |
Accession |
P52292 |
Shipping |
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20CC. |
Purity |
> 90 % as determined by reducing SDS-PAGE. |
Endotoxin |
< 1.0 EU per ug as determined by the LAL method. |
Stability and Storage |
Store at < -20CC, stable for 6 months. Please minimize freeze-thaw cycles. |
Mol Mass |
60.0 kDa |
AP Mol Mass |
60 kDa |
Formulation |
Supplied as a 0.2 um filtered solution of 20mM TrisHCl, 1mM DTT, 20% Glycerol, pH 8.0 . |
Reconstitution |
Please refer to the printed manual for detailed information. |
Background |
Karyopherin Subunit alpha-2 (KPNA2) belongs to the importin alpha family. KPNA2 is widely expressed in many tissues and contains an N-terminal hydrophilic region, a hydrophobic central region composed of 10 repeats, and a short hydrophilic C-terminus. KPNA2 interacts with the NLSs of DNA helicase Q1 and SV40 T antigen and may be involved in the nuclear transport of proteins. KPNA2 also may play a role in V(D)J recombination. KPNA2 functions in nuclear protein importantly as an adapter protein for nuclear receptor KPNB1. |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.