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Recombinant Human Complement Factor B/CFB Protein (His Tag)

Recombinant Human Complement Factor B/CFB Protein (His Tag)

Item no.	ELS-PKSH032272-50ug
Manufacturer	Elabscience
Amount	50ug
Category	Peptides & Proteins Recombinant Proteins
Type	Proteins
Specific against	Human
Host	Human Cells
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Complement Factor B, C3/C5 Convertase, Glycine-Rich Beta Glycoprotein, GBG, PBF2, Properdin Factor B, CFB, BF, BFD
Similar products	CFB, BF, BFD, GBG, PBF2, Complement Factor B, C3/C5 Convertase, Glycine-Rich Beta Glycoprotein, Properdin Factor B
Available
Synonym	Complement Factor B, C3/C5 Convertase, Glycine-Rich Beta Glycoprotein, GBG, PBF2, Properdin Factor B, CFB, BF, BFD
Storage	< -20CC
Protein Construction	Recombinant Human Complement Factor B is produced by our Mammalian expression system and the target gene encoding Thr26-Leu764 is expressed with a 6His tag at the C-terminus.
Sequence	Thr 26-Leu764
Fusion tag	C-6His
Accession	P00751
Shipping	This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20CC.
Purity	> 95 % as determined by reducing SDS-PAGE.
Endotoxin	< 1.0 EU per ug as determined by the LAL method.
Stability and Storage	Store at < -20CC, stable for 6 months. Please minimize freeze-thaw cycles.
Mol Mass	84.1 kDa
AP Mol Mass	90 kDa
Formulation	Supplied as a 0.2 um filtered solution of 20mM TrisHCl, 150mM NaCl, pH 8.0.
Reconstitution	Please refer to the printed manual for detailed information.
Background	Complement Factor B (CFB) belongs to the peptidase S1 family of enzymes. It is expressed by hepatocytes and macrophages and localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. CFB which is a component of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb. The active subunit Bb is a serine protease which associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50ug

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Delivery expected until 10/11/2024

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