Item no. |
ELS-PKSH030673-20ug |
Manufacturer |
Elabscience
|
Amount |
20ug |
Category |
|
Type |
Proteins |
Specific against |
Human |
Host |
HEK293 cells |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Alias |
Endoplasmic Reticulum Resident Protein 27, ER Protein 27, ERp27, ERP27, C12orf46 |
Similar products |
ERP27, C12orf46, ERp27, Endoplasmic Reticulum Resident Protein 27, ER Protein 27 |
Available |
|
Synonym |
Endoplasmic Reticulum Resident Protein 27, ER Protein 27, ERp27, ERP27, C12orf46 |
Storage |
according to manual |
Protein Construction |
A DNA sequence encoding the human ERP27 (Q96DN0) (Glu26-Pro269) was fused with Fc region of mouse IgG at the C-terminus. |
Sequence |
Glu26-Pro269 |
Fusion tag |
C-Fc |
Accession |
Q96DN0 |
Shipping |
This product is provided as lyophilized powder which is shipped with ice packs. |
Purity |
> 84 % as determined by reducing SDS-PAGE. |
Endotoxin |
< 1.0 EU per ug of the protein as determined by the LAL method. |
Stability and Storage |
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80CC. Reconstituted protein solution can be stored at 4-8C for 2-7 days. Aliquots of reconstituted samples are stable at < -20C for 3 months. |
Mol Mass |
53.7 kDa |
Formulation |
Lyophilized from sterile PBS; pH 7.4 |
Reconstitution |
Please refer to the printed manual for detailed information. |
Background |
ERP27 contains 1 thioredoxin domain and is a noncatalytic member of the protein disulfide isomerase family. Protein disulfide isomerases (PDIs) constitute a family of structurally related enzymes which catalyze disulfide bonds formation; reduction; or isomerization of newly synthesized proteins in the lumen of the endoplasmic reticulum (ER). They act also as chaperones; and are; therefore; part of a quality-control system for the correct folding of the proteins in the same subcellular compartment. PDI has been found to have moderate effects (25-fold) on the rate of oxidative folding of proteins in vitro. Recombinant Human Protein Disulfide Isomerase is involved in disulphide-bond formation and isomerization; as well as the reduction of disulphide bonds in proteins. Recombinant PDI has been found to have moderate effects (25-fold) on the rate of oxidative folding of proteins in vitro. ERP27 is a widely expressed protein which localizes to the ER and may act as a protease; protein disulfide isomerase; thiol-disulfide oxidase or phospholipase. ERP27 doesn't contain a CXXC active site motif indicating that it is a catalytically redox-inactive member of the protein disulfide isomerase family. |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.