Item no. |
E-AB-F1028C-50 |
Manufacturer |
Elabscience
|
Amount |
50Tests |
Category |
|
Type |
Antibody Monoclonal |
Applications |
FC |
Clone |
FGK4.5/FGK45 |
Specific against |
Mouse |
Host |
Rat |
Isotype |
IgG2a kappa |
ECLASS 10.1 |
42030590 |
ECLASS 11.0 |
42030590 |
UNSPSC |
12352203 |
Alias |
Tumor necrosis factor receptor superfamily member 5, Cd40, B-cell surface antigen CD40, Bp50, CD40L receptor, CD40, Tnfrsf5 |
Similar products |
CD40, Tumor necrosis factor receptor superfamily member 5, B-cell surface antigen CD40, Bp50, CD40L receptor, Cd40, Tnfrsf5 |
Available |
|
Synonyms |
Tumor necrosis factor receptor superfamily member 5, Cd40, B-cell surface antigen CD40, Bp50, CD40L receptor, CD40, Tnfrsf5 |
Swissprot |
P27512 |
Background |
CD40 is a 48 kD type I transmembrane glycoprotein also known as Bp50. It is a member of the tumor necrosis factor receptor (TNFR) superfamily and is expressed on B cells, basal epithelial cells, macrophages, follicular dendritic cells, endothelial cells, and a subset of CD34+ hematopoietic progenitors. CD40 regulates B cell development/maturation, Ig isotype switching and, in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with its ligand CD154 (gp39), which is expressed on activated T cells, is important in costimulation and immune regulation. |
Storage |
Store at 2ca.8C and protected from prolonged exposure to light. Do not freeze. |
Buffer |
PBS with 0.05% Proclin300, 1% BSA |
Conjugation |
FITC |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.