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AF/LE Purified Anti-Mouse F4/80 Monoclonal Antibody[CI:A3-1]

AF/LE Purified Anti-Mouse F4/80 Monoclonal Antibody[CI:A3-1]

Item no.	E-AB-F09950-50
Manufacturer	Elabscience
Amount	50ug
Category	Antibodies Flow Cytometry Immunohistochemistry Western Blot Primary Antibodies Functional Assays
Type	Antibody Monoclonal
Applications	WB, FC, IHC, Functional Assays
Clone	CI:A3-1
Specific against	Mouse (Murine, Mus musculus)
Host	Rat
Isotype	IgG2b kappa
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Adhesion G protein-coupled receptor E1, Adgre1, Cell surface glycoprotein F4/80, EGF-like module receptor 1, Adgre1, Emr1, Gpf480
Similar products	Emr1, EGF-like module receptor 1, Adhesion G protein-coupled receptor E1, Adgre1, Cell surface glycoprotein F4/80, Gpf480
Available
Synonyms	Adhesion G protein-coupled receptor E1, Adgre1, Cell surface glycoprotein F4/80, EGF-like module receptor 1, Adgre1, Emr1, Gpf480
Swissprot	Q61549
Background	F4/80 is a 160 kD glycoprotein. It is characterized as a member of the epidermal growth factor (EGF)-transmembrane 7 (TM7) family. F4/80, also known as EMR1 or Ly71, has been widely used as a murine macrophage marker, which is expressed on the majority of tissue macrophages including peritoneal macrophages, macrophages in lung, gut, thymus and red pulp of spleen (but not on the macrophages located in T cell areas of the spleen, lymph node and Peyer's patch), Kuffer cells, Langerhans cells, and bone marrow stromal cells. F4/80 has also been shown on a subset of dendritic cells. The biological ligand of F4/80 has not been identified, but it has been reported that F4/80 is required for induction of CD8+ T cells-mediated peripheral tolerance.
Concentration	0.5 mg/mL
Storage	Store at 2ca.8C. Do not freeze.
Buffer	0.2 um filtered in PBS, pH7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.
Conjugation	None (Purified antibody-Azide Free/Low endotoxin)

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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