Item no. |
E-AB-60162-200 |
Manufacturer |
Elabscience
|
Amount |
200uL |
Category |
|
Type |
Antibody Polyclonal |
Applications |
WB |
Specific against |
Human, Rat |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Aplysia RAS-related homolog 9, ARH 9, ARH9, ARHC, H9, MGC1448, MGC61427, Oncogene RHO H9, Ras homolog gene family member C, RAS related homolog 9, RHO C, Rho cDNA clone 9, Rho related GTP binding protein RhoC, Rho-related GTP-binding protein RhoC, rhoC, R |
Similar products |
RHOC, ARH9, ARHC, Rho-related GTP-binding protein RhoC, Rho cDNA clone 9, rhoC, H9, MGC1448, MGC61427, RHOH9, Oncogene RHO H9, Rho related GTP binding protein RhoC, Small GTP binding protein RhoC, ARH 9, Ras homolog gene family member C, RAS related homolog 9, RHO C, RhC GTPase, RHOH 9, Aplysia RAS-related homolog 9 |
Available |
|
Research Areas |
Cancer, Signal Transduction |
Synonyms |
Aplysia RAS-related homolog 9, ARH 9, ARH9, ARHC, H9, MGC1448, MGC61427, Oncogene RHO H9, Ras homolog gene family member C, RAS related homolog 9, RHO C, Rho cDNA clone 9, Rho related GTP binding protein RhoC, Rho-related GTP-binding protein RhoC, rhoC, RhC GTPase, RHOC, RHOH 9, RHOH9, Small GTP binding protein RhoC |
Swissprot |
P08134 |
Background |
This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The protein encoded by this gene is prenylated at its C-terminus, and localizes to the cytoplasm and plasma membrane. It is thought to be important in cell locomotion. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified. |
Concentration |
1 mg/mL |
Storage |
Store at -20C. Avoid freeze / thaw cycles. |
Immunogen |
Recombinant protein of human RHOC |
Buffer |
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. |
Purification Method |
Affinity purification |
Dilution |
WB 1:500 - 1:2000 |
Conjugation |
Unconjugated |
Calculated MW |
22kDa |
Observed MW |
22kDa |
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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.