Item no. |
E-AB-70233-200 |
Manufacturer |
Elabscience
|
Amount |
200uL |
Category |
|
Type |
Antibody Polyclonal |
Applications |
WB, IHC |
Specific against |
Human, Mouse, Rat |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
H2A histone family member X, H2A histone family member X, H2A.FX, H2A.X, H2a/x, H2AFX, H2AX, H2AX, Histone H2A.X |
Similar products |
H2AFX, H2AX, H2a/x, H2A.X, Histone H2A.X, H2A histone family member X, H2A histone family member X, H2A.FX |
Available |
|
Research Areas |
Cancer, Epigenetics and Nuclear Signaling |
Synonyms |
H2A histone family member X, H2A histone family member X, H2A.FX, H2A.X, H2a/x, H2AFX, H2AX, H2AX, Histone H2A.X |
Swissprot |
P16104, P27661 |
Background |
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif. |
Concentration |
0.86 mg/mL |
Storage |
Store at -20C. Avoid freeze / thaw cycles. |
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse Histone H2A.X |
Buffer |
PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4 |
Purification Method |
Affinity purification |
Dilution |
WB 1:500-1:2000, IHC 1:300-1:800 |
Conjugation |
Unconjugated |
Calculated MW |
15-18kDa |
Observed MW |
18kDa |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.