Item no. |
E-AB-65513-200 |
Manufacturer |
Elabscience
|
Amount |
200uL |
Category |
|
Type |
Antibody Polyclonal |
Applications |
WB |
Specific against |
Human, Mouse, Rat |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Acidic-type mitochondrial creatine kinase, CKMT, CKMT1, CKMT1B, Creatine kinase mitochondrial 1 (ubiquitous), Creatine kinase mitochondrial 1B, Creatine kinase U type mitochondrial, Creatine kinase U-type, KCRU, Mia-CK, mitochondrial, U-MtCK, Ubiquitous m |
Similar products |
CKMT1B, mitochondrial, CKMT, Creatine kinase U-type, Acidic-type mitochondrial creatine kinase, Ubiquitous mitochondrial creatine kinase, CKMT1, UMTCK, KCRU, Mia-CK, U-MtCK, Creatine kinase mitochondrial 1 (ubiquitous), Creatine kinase mitochondrial 1B, Creatine kinase U type mitochondrial |
Available |
|
Synonyms |
Acidic-type mitochondrial creatine kinase, CKMT, CKMT1, CKMT1B, Creatine kinase mitochondrial 1 (ubiquitous), Creatine kinase mitochondrial 1B, Creatine kinase U type mitochondrial, Creatine kinase U-type, KCRU, Mia-CK, mitochondrial, U-MtCK, Ubiquitous mitochondrial creatine kinase, UMTCK |
Swissprot |
P12532 |
Background |
Mitochondrial creatine (MtCK) kinase is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase; this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis. Ubiquitous mitochondrial creatine kinase has 80% homology with the coding exons of sarcomeric mitochondrial creatine kinase. Two genes located near each other on chromosome 15 have been identified which encode identical mitochondrial creatine kinase proteins. |
Concentration |
1 mg/mL |
Storage |
Store at -20C. Avoid freeze / thaw cycles. |
Immunogen |
Recombinant protein of human CKMT1A |
Buffer |
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. |
Purification Method |
Affinity purification |
Dilution |
WB 1:500 - 1:2000 |
Conjugation |
Unconjugated |
Calculated MW |
47kDa/50kDa |
Observed MW |
47kDa |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.