TBL1X Polyclonal Antibody

EBI, F box like/WD repeat protein TBL1X, F-box-like/WD repeat-containing protein TBL1X, SMAP 55, SMAP55, TBL 1, TBL 1X, TBL1, TBL1X, TBL1X, Transducin (beta) like 1, Transducin (beta) like 1 X linked, Transducin (beta) like 1X linked, Transducin beta like 1 X linked, Transducin beta like 1X, Transducin beta like 1X protein, Transducin beta like protein 1, X linked, Transducin beta-like protein 1X, Transducin-beta-like protein 1, X-linked

The protein encoded by this gene has sequence similarity with members of the WD40 repeat-containing protein family. The WD40 group is a large family of proteins, which appear to have a regulatory function. It is believed that the WD40 repeats mediate protein-protein interactions and members of the family are involved in signal transduction, RNA processing, gene regulation, vesicular trafficking, cytoskeletal assembly and may play a role in the control of cytotypic differentiation. This encoded protein is found as a subunit in corepressor SMRT (silencing mediator for retinoid and thyroid receptors) complex along with histone deacetylase 3 protein. This gene is located adjacent to the ocular albinism gene and it is thought to be involved in the pathogenesis of the ocular albinism with late-onset sensorineural deafness phenotype. Four transcript variants encoding two different isoforms have been found for this gene. This gene is highly similar to the Y chromosome TBL1Y gene.

Store at -20C. Avoid freeze / thaw cycles.

PBS with 0.02% sodium azide and 50% glycerol pH 7.4.

WB 1:500 - 1:2000

57kDa/62kDa