Item no. |
E-AB-64635-60 |
Manufacturer |
Elabscience
|
Amount |
60uL |
Category |
|
Type |
Antibody Polyclonal |
Applications |
WB, IF |
Specific against |
Human, Mouse, Rat |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
2810024C04Rik, DNA repair protein rad18, E3 ubiquitin-protein ligase RAD18, EC 6.3.2.-, hHR 18, hHR18, hRAD 18, hRAD18, MGC156682, Postreplication repair E3 ubiquitin-protein ligase RAD18, Postreplication repair protein hRAD18p, Postreplication repair pro |
Similar products |
RAD18, RNF73, Structural maintenance of chromosomes protein 6, E3 ubiquitin-protein ligase RAD18, Postreplication repair protein RAD18, hHR18, hRAD18, RING finger protein 73, EC 6.3.2.-, 2810024C04Rik, DNA repair protein rad18, hHR 18, hRAD 18, MGC156682, Postreplication repair E3 ubiquitin-protein ligase RAD18, Postreplication repair protein hRAD18p, RAD 18, RAD18 homolog (S. cerevisiae), RAD18 homolog, RAD18 S. cerevisiae homolog, RAD18 S. cerevisiae homolog of, RAD18 transcript variant, Rad18sc, Radiation sensitivity protein 18, RNF 73, YCR066W, YCR66W |
Available |
|
Research Areas |
Cancer, Cell Biology, Epigenetics and Nuclear Signaling |
Synonyms |
2810024C04Rik, DNA repair protein rad18, E3 ubiquitin-protein ligase RAD18, EC 6.3.2.-, hHR 18, hHR18, hRAD 18, hRAD18, MGC156682, Postreplication repair E3 ubiquitin-protein ligase RAD18, Postreplication repair protein hRAD18p, Postreplication repair protein RAD18, RAD 18, RAD18, RAD18 homolog (S. cerevisiae), RAD18 homolog, RAD18 S. cerevisiae homolog, RAD18 S. cerevisiae homolog of, RAD18 transcript variant, RAD18, Rad18sc, Radiation sensitivity protein 18, RING finger protein 73, RNF 73, RNF73, Structural maintenance of chromosomes protein 6, YCR066W, YCR66W |
Swissprot |
Q9NS91 |
Background |
The protein encoded by this gene is highly similar to S. cerevisiae DNA damage repair protein Rad18. Yeast Rad18 functions through its interaction with Rad6, which is an ubiquitin-conjugating enzyme required for post-replication repair of damaged DNA. Similar to its yeast counterpart, this protein is able to interact with the human homolog of yeast Rad6 protein through a conserved ring-finger motif. Mutation of this motif results in defective replication of UV-damaged DNA and hypersensitivity to multiple mutagens. |
Concentration |
1 mg/mL |
Storage |
Store at -20C. Avoid freeze / thaw cycles. |
Immunogen |
Recombinant protein of human RAD18 |
Buffer |
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. |
Purification Method |
Affinity purification |
Dilution |
WB 1:500 - 1:2000 IF 1:50 - 1:200 |
Conjugation |
Unconjugated |
Calculated MW |
56kDa |
Observed MW |
80kDa |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.