CEBP alpha Polyclonal Antibody

Apoptotic cysteine protease, Apoptotic protease Mch 5, C/EBP alpha, C/ebpalpha, CAP4, Caspase 8 precursor, CBF-A, CCAAT Enhancer Binding Protein alpha, CCAAT/enhancer binding protein (C/EBP), alpha, CCAAT/enhancer-binding protein alpha, CEBP, CEBP A, CEBP alpha, Cebpa, CEBPA, FADD homologous ICE/CED 3 like protease, FADD like ICE, FLICE, ICE like apoptotic protease 5, ICE8, MACH, MCH5, MORT1 associated CED 3 homolog

This intronless gene encodes a transcription factor that contains a basic leucine zipper (bZIP) domain and recognizes the CCAAT motif in the promoters of target genes. The encoded protein functions in homodimers and also heterodimers with CCAAT/enhancer-binding proteins beta and gamma. Activity of this protein can modulate the expression of genes involved in cell cycle regulation as well as in body weight homeostasis. Mutation of this gene is associated with acute myeloid leukemia. The use of alternative in-frame non-AUG (GUG) and AUG start codons results in protein isoforms with different lengths. Differential translation initiation is mediated by an out-of-frame, upstream open reading frame which is located between the GUG and the first AUG start codons.

Store at -20C. Avoid freeze / thaw cycles.

PBS with 0.02% sodium azide and 50% glycerol pH 7.4.

WB 1:500 - 1:2000 IHC 1:50 - 1:200

25kDa/35kDa/37kDa/41kDa