Item no. |
E-AB-63750-60 |
Manufacturer |
Elabscience
|
Amount |
60uL |
Category |
|
Type |
Antibody Polyclonal |
Applications |
WB |
Specific against |
Human, Mouse, Rat |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
ALDB, ALDO B, ALDO2, ALDOB, ALDOB, Aldolase 2, Aldolase B, Aldolase B fructose bisphosphate, Aldolase2, AldolaseB, EC 4.1.2.13, Fructose bisphosphate aldolase B, Fructose-bisphosphate aldolase B, Liver type aldolase, Liver-type aldolase, MS1077 |
Similar products |
ALDOB, ALDB, Fructose-bisphosphate aldolase B, Liver-type aldolase, ALDO2, Aldolase B, ALDO B, Aldolase 2, Aldolase B fructose bisphosphate, Aldolase2, AldolaseB, EC 4.1.2.13, Fructose bisphosphate aldolase B, Liver type aldolase, MS1077 |
Available |
|
Research Areas |
Cancer, Metabolism, Signal Transduction |
Synonyms |
ALDB, ALDO B, ALDO2, ALDOB, ALDOB, Aldolase 2, Aldolase B, Aldolase B fructose bisphosphate, Aldolase2, AldolaseB, EC 4.1.2.13, Fructose bisphosphate aldolase B, Fructose-bisphosphate aldolase B, Liver type aldolase, Liver-type aldolase, MS1077 |
Swissprot |
P05062 |
Background |
Fructose-1, 6-bisphosphate aldolase (EC 4.1.2.13) is a tetrameric glycolytic enzyme that catalyzes the reversible conversion of fructose-1, 6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Vertebrates have 3 aldolase isozymes which are distinguished by their electrophoretic and catalytic properties. Differences indicate that aldolases A, B, and C are distinct proteins, the products of a family of related 'housekeeping' genes exhibiting developmentally regulated expression of the different isozymes. The developing embryo produces aldolase A, which is produced in even greater amounts in adult muscle where it can be as much as 5% of total cellular protein. In adult liver, kidney and intestine, aldolase A expression is repressed and aldolase B is produced. In brain and other nervous tissue, aldolase A and C are expressed about equally. There is a high degree of homology between aldolase A and C. Defects in ALDOB cause hereditary fructose intolerance. |
Concentration |
1 mg/mL |
Storage |
Store at -20C. Avoid freeze / thaw cycles. |
Immunogen |
Recombinant protein of human ALDOB |
Buffer |
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. |
Purification Method |
Affinity purification |
Dilution |
WB 1:1000 - 1:2000 |
Conjugation |
Unconjugated |
Calculated MW |
39kDa |
Observed MW |
39kDa |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.