Item no. |
E-AB-61425-120 |
Manufacturer |
Elabscience
|
Amount |
120uL |
Category |
|
Type |
Antibody Polyclonal |
Applications |
WB, IF |
Specific against |
Human, Mouse, Rat |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
190 kDa paraneoplastic pemphigus antigen, 195 kDa cornified envelope precursor, 195 kDa cornified envelope precursor protein, AW553870, KIAA0568, MGC134872 , PEPL, Periplakin, ppl |
Similar products |
KIAA0568, Periplakin, 190 kDa paraneoplastic pemphigus antigen, 195 kDa cornified envelope precursor protein, MGC134872, PEPL, ppl, 195 kDa cornified envelope precursor, AW553870 |
Available |
|
Research Areas |
Immunology, Signal Transduction |
Synonyms |
190 kDa paraneoplastic pemphigus antigen, 195 kDa cornified envelope precursor, 195 kDa cornified envelope precursor protein, AW553870, KIAA0568, MGC134872 , PEPL, Periplakin, ppl |
Swissprot |
O60437 |
Background |
The protein encoded by this gene is a component of desmosomes and of the epidermal cornified envelope in keratinocytes. The N-terminal domain of this protein interacts with the plasma membrane and its C-terminus interacts with intermediate filaments. Through its rod domain, this protein forms complexes with envoplakin. This protein may serve as a link between the cornified envelope and desmosomes as well as intermediate filaments. AKT1/PKB, a protein kinase mediating a variety of cell growth and survival signaling processes, is reported to interact with this protein, suggesting a possible role for this protein as a localization signal in AKT1-mediated signaling. |
Concentration |
1 mg/mL |
Storage |
Store at -20C. Avoid freeze / thaw cycles. |
Immunogen |
Recombinant protein of human PPL |
Buffer |
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. |
Purification Method |
Affinity purification |
Dilution |
WB 1:500 - 1:2000 IF 1:50 - 1:100 |
Conjugation |
Unconjugated |
Calculated MW |
204kDa |
Observed MW |
205kDa |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.