Manufacturer |
Elabscience
|
Category |
|
Type |
Antibody Polyclonal |
Specific against |
Human, Mouse, Rat |
Isotype |
IgG |
Applications |
WB, IP |
Amount |
120uL |
Host |
Rabbit |
Item no. |
E-AB-61367-120 |
eClass 6.1 |
32160702 |
eClass 9.0 |
32160702 |
Available |
|
Alias |
CMTDIC, SYYC, Tyrosine tRNA ligase, cytoplasmic, Tyrosine tRNA ligase 1, cytoplasmic, Tyrosyl tRNA synthetase, Tyrosyl--tRNA ligase, Tyrosyl-tRNA synthetase, cytoplasmic, TyrRS, yars, YRS, YTS |
Research Areas |
Cancer, Epigenetics and Nuclear Signaling |
Synonyms |
CMTDIC, SYYC, Tyrosine tRNA ligase, cytoplasmic, Tyrosine tRNA ligase 1, cytoplasmic, Tyrosyl tRNA synthetase, Tyrosyl--tRNA ligase, Tyrosyl-tRNA synthetase, cytoplasmic, TyrRS, yars, YRS, YTS |
Swissprot |
P54577 |
Background |
Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Tyrosyl-tRNA synthetase belongs to the class I tRNA synthetase family. Cytokine activities have also been observed for the human tyrosyl-tRNA synthetase, after it is split into two parts, an N-terminal fragment that harbors the catalytic site and a C-terminal fragment found only in the mammalian enzyme. The N-terminal fragment is an interleukin-8-like cytokine, whereas the released C-terminal fragment is an EMAP II-like cytokine. |
Concentration |
1 mg/mL |
Storage |
Store at -20C. Avoid freeze / thaw cycles. |
Immunogen |
Recombinant protein of human YARS |
Buffer |
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. |
Purification Method |
Affinity purification |
Dilution |
WB 1:500 - 1:2000 IP 1:50 - 1:200 |
Conjugation |
Unconjugated |
Calculated MW |
59kDa |
Observed MW |
59kDa |
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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.