Item no. |
E-AB-61284-120 |
Manufacturer |
Elabscience
|
Amount |
120uL |
Category |
|
Type |
Antibody Polyclonal |
Applications |
WB, IF |
Specific against |
Human, Mouse, Rat |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
HSPK 36, NEK3, NEK3, Never in mitosis A-related kinase 3, NIMA (never in mitosis gene a) related kinase 3, NimA related protein kinase 3, NimA-related protein kinase 3, Serine/threonine protein kinase Nek3, Serine/threonine-protein kinase Nek3 |
Similar products |
NEK3, Serine/threonine-protein kinase Nek3, Never in mitosis A-related kinase 3, HSPK 36, NimA related protein kinase 3, NimA-related protein kinase 3, Serine/threonine protein kinase Nek3, NIMA (never in mitosis gene a) related kinase 3 |
Available |
|
Research Areas |
Cancer, Signal Transduction |
Synonyms |
HSPK 36, NEK3, NEK3, Never in mitosis A-related kinase 3, NIMA (never in mitosis gene a) related kinase 3, NimA related protein kinase 3, NimA-related protein kinase 3, Serine/threonine protein kinase Nek3, Serine/threonine-protein kinase Nek3 |
Swissprot |
P51956 |
Background |
This gene encodes a member of the NimA (never in mitosis A) family of serine/threonine protein kinases. The encoded protein differs from other NimA family members in that it is not cell cycle regulated and is found primarily in the cytoplasm. The kinase is activated by prolactin stimulation, leading to phosphorylation of VAV2 guanine nucleotide exchange factor, paxillin, and activation of the RAC1 GTPase. Multiple transcript variants encoding different isoforms have been found for this gene. |
Concentration |
1 mg/mL |
Storage |
Store at -20C. Avoid freeze / thaw cycles. |
Immunogen |
Recombinant protein of human NEK3 |
Buffer |
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. |
Purification Method |
Affinity purification |
Dilution |
WB 1:500 - 1:2000 IF 1:50 - 1:200 |
Conjugation |
Unconjugated |
Calculated MW |
55kDa/57kDa |
Observed MW |
55kDa |
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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.