PSMB2 Polyclonal Antibody

HC7 I, Macropain subunit C7 I, Macropain subunit C7-I, Multicatalytic endopeptidase complex subunit C7 1 , Multicatalytic endopeptidase complex subunit C7 I , Multicatalytic endopeptidase complex subunit C7-I, Proteasome (prosome, macropain) subunit beta type 2, Proteasome beta 2 subunit , Proteasome component C7 I, Proteasome component C7-I, Proteasome subunit beta type-2, PSB2, Psmb2

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Store at -20C. Avoid freeze / thaw cycles.

PBS with 0.02% sodium azide and 50% glycerol pH 7.4.

WB 1:500 - 1:2000 IF 1:50 - 1:200

22kDa