Item no. |
E-AB-60805-120 |
Manufacturer |
Elabscience
|
Amount |
120uL |
Category |
|
Type |
Antibody Polyclonal |
Applications |
WB |
Specific against |
Human, Mouse, Rat |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
67 kDa glutamic acid decarboxylase, CPSQ1, DCE1, DCE1, EC 4.1.1.15, FLJ45882, GAD 67, GAD, GAD-67, GAD1, Glutamate decarboxylase 1 (brain, 67kDa), Glutamate decarboxylase 1, Glutamate decarboxylase 1 brain 67kD, Glutamate decarboxylase 1 brain 67kDa, Glut |
Similar products |
GAD-67, GAD1, GAD, Glutamate decarboxylase 1, 67 kDa glutamic acid decarboxylase, Glutamate decarboxylase 67 kDa isoform, brain, FLJ45882, SCP, CPSQ1, Glutamate decarboxylase, DCE1, DCE1, EC 4.1.1.15, GAD 67, Glutamate decarboxylase 1 (brain, 67kDa), Glutamate decarboxylase 1 brain 67kD, Glutamate decarboxylase 1 brain 67kDa, 67-KD, OTTHUMP00000041055 |
Available |
|
Research Areas |
Cancer, Metabolism, Immunology, Signal Transduction |
Synonyms |
67 kDa glutamic acid decarboxylase, CPSQ1, DCE1, DCE1, EC 4.1.1.15, FLJ45882, GAD 67, GAD, GAD-67, GAD1, Glutamate decarboxylase 1 (brain, 67kDa), Glutamate decarboxylase 1, Glutamate decarboxylase 1 brain 67kD, Glutamate decarboxylase 1 brain 67kDa, Glutamate decarboxylase 67 kDa isoform, Glutamate decarboxylase, brain, 67-KD, OTTHUMP00000041055, SCP |
Swissprot |
Q99259 |
Background |
This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures. Alternative splicing of this gene results in two products, the predominant 67-kD form and a less-frequent 25-kD form. |
Concentration |
1 mg/mL |
Storage |
Store at -20C. Avoid freeze / thaw cycles. |
Immunogen |
Recombinant protein of human GAD1 |
Buffer |
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. |
Purification Method |
Affinity purification |
Dilution |
WB 1:500 - 1:2000 |
Conjugation |
Unconjugated |
Calculated MW |
25kDa/47kDa/66kDa |
Observed MW |
67kDa |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.