Item no. |
E-AB-52886-20 |
Manufacturer |
Elabscience
|
Amount |
20uL |
Category |
|
Type |
Antibody Polyclonal |
Applications |
IHC, ELISA |
Specific against |
Human, Mouse, Rat |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Dual specificity phosphatase 7, Dual specificity protein phosphatase 7, Dual specificity protein phosphatase PYST2, DUS7, Dusp7, Jnk Stimulatory Phosphatase 1, JSP1, MAP kinase phosphatase X, MKPX, PYST2 |
Similar products |
Dusp7, JSP1, MKPX, PYST2, Dual specificity protein phosphatase 7, Dual specificity protein phosphatase PYST2, DUS7, Jnk Stimulatory Phosphatase 1, Dual specificity phosphatase 7, MAP kinase phosphatase X |
Available |
|
Research Areas |
Cell Biology, Epigenetics and Nuclear Signaling |
Synonyms |
Dual specificity phosphatase 7, Dual specificity protein phosphatase 7, Dual specificity protein phosphatase PYST2, DUS7, Dusp7, Jnk Stimulatory Phosphatase 1, JSP1, MAP kinase phosphatase X, MKPX, PYST2 |
Swissprot |
Q16829 |
Background |
Dual-specificity phosphatases (DUSPs) constitute a large heterogeneous subgroup of the type I cysteine-based protein-tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both tyrosine and serine/threonine residues. DUSP7 belongs to a class of DUSPs, designated MKPs, that dephosphorylate MAPK (mitogen-activated protein kinase) proteins ERK (see MIM 601795), JNK (see MIM 601158), and p38 (see MIM 600289) with specificity distinct from that of individual MKP proteins. MKPs contain a highly conserved C-terminal catalytic domain and an N-terminal Cdc25 (see MIM 116947)-like (CH2) domain. MAPK activation cascades mediate various physiologic processes, including cellular proliferation, apoptosis, differentiation, and stress responses (summary by Patterson et al., 2009 [PubMed 19228121]). |
Concentration |
0.66 mg/mL |
Storage |
Store at -20C. Avoid freeze / thaw cycles. |
Immunogen |
Fusion protein of human DUSP7 |
Buffer |
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4 |
Purification Method |
Antigen affinity purification |
Dilution |
IHC 1:50-1:300, ELISA 1:5000-1:10000 |
Conjugation |
Unconjugated |
Gene Accession |
BC019107 |
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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.