Item no. |
E-AB-22105-60 |
Manufacturer |
Elabscience
|
Amount |
60uL |
Category |
|
Type |
Antibody Monoclonal |
Applications |
IF, IHC-P |
Clone |
1A5 |
Specific against |
Human, Mouse, Rat |
Host |
Mouse |
Isotype |
IgG |
ECLASS 10.1 |
42030590 |
ECLASS 11.0 |
42030590 |
UNSPSC |
12352203 |
Alias |
NR3C3, Nuclear receptor subfamily 3 group C member 3, PGR, PR, PRA, PRB, PRGR, Progesterone receptor, Progestin receptor form A, Progestin receptor form B |
Similar products |
PR, PGR, NR3C3, Progesterone receptor, Nuclear receptor subfamily 3 group C member 3, PRB, PRA, Progestin receptor form A, Progestin receptor form B, Progestin receptor form A, PRGR |
Available |
|
Research Areas |
Cancer, Epigenetics and Nuclear Signaling, Neuroscience, Signal Transduction |
Synonyms |
NR3C3, Nuclear receptor subfamily 3 group C member 3, PGR, PR, PRA, PRB, PRGR, Progesterone receptor, Progestin receptor form A, Progestin receptor form B |
Swissprot |
P06401 |
Background |
The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Progesterone receptor isoform B (PRB) is involved activation of c-SRC/MAPK signaling on hormone stimulation.Isoform A: inactive in stimulating c-Src/MAPK signaling on hormone stimulation.Isoform 4: Increases mitochondrial membrane potential and cellular respiration upon stimulation by progesterone. |
Concentration |
1 mg/mL |
Storage |
Store at -20C. Avoid freeze / thaw cycles. |
Immunogen |
Synthetic Peptide |
Buffer |
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. |
Purification Method |
Protein A purification |
Dilution |
IHC 1:100-1:300, IF 1:100-200 |
Conjugation |
Unconjugated |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.