Item no. |
E-AB-20883-20 |
Manufacturer |
Elabscience
|
Amount |
20uL |
Category |
|
Type |
Antibody Polyclonal |
Applications |
WB, ELISA |
Specific against |
Human, Mouse, Rat |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
ARHGAP35, GAP associated protein p190, Glucocorticoid receptor DNA binding factor 1, Glucocorticoid receptor DNA-binding factor 1, Glucocorticoid receptor repression factor 1, GRF 1, GRF-1, GRF1, GRLF 1, GRLF1, GRLF1, KIAA1722, MGC10745, p190 A, p190-A, P |
Similar products |
GRLF1, rat, ARHGAP35, GRF1, homolog of, GRF-1, KIAA1722, MGC10745, P190A, p190RhoGAP, Rho GTPase-activating protein 35, Glucocorticoid receptor DNA-binding factor 1, Glucocorticoid receptor repression factor 1, Rho GAP p190A, p190-A, p190ARhoGAP, GAP associated protein p190, Glucocorticoid receptor DNA binding factor 1, GRF 1, GRLF 1, p190 A |
Available |
|
Research Areas |
Epigenetics and Nuclear Signaling |
Synonyms |
ARHGAP35, GAP associated protein p190, Glucocorticoid receptor DNA binding factor 1, Glucocorticoid receptor DNA-binding factor 1, Glucocorticoid receptor repression factor 1, GRF 1, GRF-1, GRF1, GRLF 1, GRLF1, GRLF1, KIAA1722, MGC10745, p190 A, p190-A, P190A, P190A, rat, homolog of, p190ARhoGAP, p190RhoGAP, Rho GAP p190A, Rho GTPase-activating protein 35 |
Swissprot |
Q9NRY4 |
Background |
The human glucocorticoid receptor DNA binding factor, which associates with the promoter region of the glucocorticoid receptor gene (hGR gene), is a repressor of glucocorticoid receptor transcription. The amino acid sequence deduced from the cDNA sequences show the presence of three sequence motifs characteristic of a zinc finger and one motif suggestive of a leucine zipper in which 1 cysteine is found instead of all leucines. The GRLF1 enhances the homologous down-regulation of wild-type hGR gene expression. Biochemical analysis suggests that GRLF1 interaction is sequence specific and that transcriptional efficacy of GRLF1 is regulated through its interaction with specific sequence motif. The level of expression is regulated by glucocorticoids. |
Concentration |
1 mg/mL |
Storage |
Store at -20C. Avoid freeze / thaw cycles. |
Immunogen |
Synthesized peptide derived from human GRF-1 around the phosphorylation site of Y1087. |
Buffer |
PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4 |
Purification Method |
Affinity purification |
Dilution |
WB 1:500-1:2000, ELISA 1:10000 |
Conjugation |
Unconjugated |
Calculated MW |
172kDa |
Observed MW |
190kDa |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.