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HUWE1 Polyclonal Antibody

HUWE1 Polyclonal Antibody

Item no.	E-AB-19540-20
Manufacturer	Elabscience
Amount	20uL
Category	Oncology Neuroscience Aging & Neurological Disorders Antibodies By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Cell Biology Cell Status Mesothelioma Immunohistochemistry ELISA Autophagy Senescence Primary Antibodies By Organ Lung Cancer
Type	Antibody Polyclonal
Applications	IHC, ELISA
Specific against	Human, Mouse, Rat
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	ARF binding protein 1, ARF BP1, ARF-binding protein 1, ARF-BP1, BJ-HCC-24 tumor antigen, E3 ubiquitin protein ligase HUWE1, E3 ubiquitin-protein ligase HUWE1, HECT, HECT domain protein LASU1, HECT UBA and WWE domain containing protein 1, HectH9, Homologou
Similar products	ARF-BP1, HECT, ARF-binding protein 1, HUWE1, Huwe1, Ib772, LASU1, UREB1, ARF binding protein 1, BJ-HCC-24 tumor antigen, HECT domain protein LASU1, Mcl-1 ubiquitin ligase E3, ARF BP1, E3 ubiquitin protein ligase HUWE1, E3 ubiquitin-protein ligase HUWE1, HECT UBA and WWE domain containing protein 1, HectH9, Homologous to E6AP carboxyl terminus homologous protein 9, Large structure of UREB1, Mcl 1 ubiquitin ligase E3, UBA and WWE domain-containing protein 1, Upstream regulatory element-binding protein 1, URE-B1, URE-binding protein 1, Mule
Available
Research Areas	Cancer, Cell Biology
Synonyms	ARF binding protein 1, ARF BP1, ARF-binding protein 1, ARF-BP1, BJ-HCC-24 tumor antigen, E3 ubiquitin protein ligase HUWE1, E3 ubiquitin-protein ligase HUWE1, HECT, HECT domain protein LASU1, HECT UBA and WWE domain containing protein 1, HectH9, Homologous to E6AP carboxyl terminus homologous protein 9, Huwe1, HUWE1, Ib772, Large structure of UREB1, LASU1, Mcl 1 ubiquitin ligase E3, Mcl-1 ubiquitin ligase E3, Mule, UBA and WWE domain-containing protein 1, Upstream regulatory element-binding protein 1, URE-B1, URE-binding protein 1, UREB1
Swissprot	Q7Z6Z7
Background	This gene encodes a protein containing a C-terminal HECT (E6AP type E3 ubiquitin protein ligase) domain that functions as an E3 ubiquitin ligase. The encoded protein is required for the ubiquitination and subsequent degradation of the anti-apoptotic protein Mcl1 (myeloid cell leukemia sequence 1 (BCL2-related)). This protein also ubiquitinates the p53 tumor suppressor, core histones, and DNA polymerase beta. Mutations in this gene are associated with Turner type X-linked syndromic mental retardation.
Concentration	0.8 mg/mL
Storage	Store at -20C. Avoid freeze / thaw cycles.
Immunogen	Synthetic peptide of human HUWE1
Buffer	PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Purification Method	Antigen affinity purification
Dilution	IHC 1:10-1:50, ELISA 1:5000-1:10000
Conjugation	Unconjugated
Gene Accession	NP113584

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 20uL

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Delivery expected until 9/6/2024

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