Manufacturer |
Elabscience
|
Category |
|
Type |
Antibody Polyclonal |
Specific against |
Human, Mouse, Rat |
Isotype |
IgG |
Applications |
IHC, ELISA |
Amount |
200uL |
Host |
Rabbit |
Item no. |
E-AB-19365-200 |
eClass 6.1 |
32160702 |
eClass 9.0 |
32160702 |
Available |
|
Alias |
PHA 2B, PHA2B, PRKWNK 4, PRKWNK4, Protein kinase lysine deficient 4, Protein kinase lysine-deficient 4, Protein kinase with no lysine 4, Serine/threonine protein kinase WNK4, Serine/threonine-protein kinase WNK4, WNK lysine deficient protein kinase 4, Wnk |
Research Areas |
Signal transduction |
Synonyms |
PHA 2B, PHA2B, PRKWNK 4, PRKWNK4, Protein kinase lysine deficient 4, Protein kinase lysine-deficient 4, Protein kinase with no lysine 4, Serine/threonine protein kinase WNK4, Serine/threonine-protein kinase WNK4, WNK lysine deficient protein kinase 4, Wnk4, WNK4 |
Swissprot |
Q96J92 |
Background |
This gene encodes a member of the WNK family of serine-threonine protein kinases. The kinase is part of the tight junction complex in kidney cells, and regulates the balance between NaCl reabsorption and K(+) secretion. The kinase regulates the activities of several types of ion channels, cotransporters, and exchangers involved in electrolyte flux in epithelial cells. Mutations in this gene result in pseudohypoaldosteronism type IIB. |
Concentration |
1.32 mg/mL |
Storage |
Store at -20C. Avoid freeze / thaw cycles. |
Immunogen |
Synthetic peptide of human WNK4 |
Buffer |
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4 |
Purification Method |
Antigen affinity purification |
Dilution |
IHC 1:40-1:200, ELISA 1:5000-1:10000 |
Conjugation |
Unconjugated |
Gene Accession |
NP115763 |
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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.