Item no. |
E-AB-18540-60 |
Manufacturer |
Elabscience
|
Amount |
60uL |
Category |
|
Type |
Antibody Polyclonal |
Applications |
WB, IHC, ELISA |
Specific against |
Human, Mouse, Rat |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
AGM4, B cell adapter containing SH2 domain protein, B cell adapter containing Src homology 2 domain protein, B cell adaptor containing SH2 domain, B cell linker, B cell linker protein, B cell-specific adaptor protein, B-cell activation, B-cell adapter con |
Similar products |
BLNK, BASH, SLP65, B-cell linker protein, B-cell adapter containing a SH2 domain protein, B-cell adapter containing a Src homology 2 domain protein, Cytoplasmic adapter protein, Src homology 2 domain-containing leukocyte protein of 65 kDa, MGC111051, SLP-65, B cell linker protein, 65-KD, AGM4, B cell adapter containing SH2 domain protein, B cell adapter containing Src homology 2 domain protein, B cell linker, Bca, Bca, BLNK s, Ly 57, Ly57, Lymphocyte antigen 57, Lyw 57, Lyw57, SLP 65, B cell adaptor containing SH2 domain, B cell-specific adaptor protein, B-cell activation, SH2 domain-containing leukocyte protein, Src homology [SH2] domain-containing leukocyte protein of 65 kD, Src homology 2 domain containing leukocyte protein of 65 kDa |
Available |
|
Research Areas |
Immunology, Signal Transduction |
Synonyms |
AGM4, B cell adapter containing SH2 domain protein, B cell adapter containing Src homology 2 domain protein, B cell adaptor containing SH2 domain, B cell linker, B cell linker protein, B cell-specific adaptor protein, B-cell activation, B-cell adapter containing a SH2 domain protein, B-cell adapter containing a Src homology 2 domain protein, B-cell linker protein, BASH, Bca, BLNK, BLNK s, BLNK, Cytoplasmic adapter protein, Ly 57, Ly57, Lymphocyte antigen 57, Lyw 57, Lyw57, MGC111051, SH2 domain-containing leukocyte protein, 65-KD, SLP 65, SLP-65, SLP65, Src homology [SH2] domain-containing leukocyte protein of 65 kD, Src homology 2 domain containing leukocyte protein of 65 kDa, Src homology 2 domain-containing leukocyte protein of 65 kDa |
Swissprot |
Q8WV28 |
Background |
This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia. |
Concentration |
1.02 mg/mL |
Storage |
Store at -20C. Avoid freeze / thaw cycles. |
Immunogen |
Fusion protein of human BLNK |
Buffer |
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4 |
Purification Method |
Antigen affinity purification |
Dilution |
WB 1:500-1:2000, IHC 1:40-1:200, ELISA 1:5000-1:10000 |
Conjugation |
Unconjugated |
Calculated MW |
50 kDa |
Observed MW |
Refer to figures |
Gene Accession |
BC018906 |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.