Item no. |
E-AB-15211-200 |
Manufacturer |
Elabscience
|
Amount |
200uL |
Category |
|
Type |
Antibody Polyclonal |
Applications |
IHC, ELISA |
Specific against |
Human, Mouse, Rat |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 5.1 |
32160702 |
ECLASS 6.1 |
32160702 |
ECLASS 8.0 |
32160702 |
ECLASS 9.0 |
32160702 |
ECLASS 10.0.1 |
32160702 |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
AT like disease, Ataxia telangiectasia disorder like, ATLD, DNA recombination and repair protein, Double strand break repair protein MRE11A, Double-strand break repair protein MRE11A, endo/exonuclease Mre11, HNGS1, meiotic recombination (S. cerevisiae) 11 |
Similar products |
MRE11, MRE11A, ATLD, HNGS1, DNA recombination and repair protein, endo/exonuclease Mre11, Double-strand break repair protein MRE11A, Meiotic recombination 11 homolog 1, MRE11 homolog 1, Meiotic recombination 11 homolog A, MRE11 homolog A, Mre 11, MRE 11a, MRE 11b, MRE11 meiotic recombination 11 homolog A, MRE11b, AT like disease, Ataxia telangiectasia disorder like, Double strand break repair protein MRE11A, MmMRE11A, meiotic recombination (S. cerevisiae) 11 homolog A, meiotic recombination 11 homolog A (S. cerevisiae), MRE11 homolog double strand break repair nuclease, MRE11 meiotic recombination 11 homolog A (S. cerevisiae), OTTHUMP00000236830, OTTHUMP00000236831, OTTHUMP00000236832, OTTHUMP00000236833 |
Available |
|
Research Areas |
Cancer, Epigenetics and Nuclear Signaling |
Synonyms |
AT like disease, Ataxia telangiectasia disorder like, ATLD, DNA recombination and repair protein, Double strand break repair protein MRE11A, Double-strand break repair protein MRE11A, endo/exonuclease Mre11, HNGS1, meiotic recombination (S. cerevisiae) 11 homolog A, Meiotic recombination 11 homolog 1, meiotic recombination 11 homolog A (S. cerevisiae), Meiotic recombination 11 homolog A, MmMRE11A, Mre 11, MRE 11a, MRE 11b, MRE11 homolog 1, MRE11 homolog A, MRE11 homolog double strand break repair nuclease, MRE11 meiotic recombination 11 homolog A (S. cerevisiae), MRE11 meiotic recombination 11 homolog A, MRE11, MRE11A, MRE11b, OTTHUMP00000236830, OTTHUMP00000236831, OTTHUMP00000236832, OTTHUMP00000236833 |
Swissprot |
P49959 |
Background |
This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms. |
Concentration |
0.5 mg/mL |
Storage |
Store at -20C. Avoid freeze / thaw cycles. |
Immunogen |
Recombinant protein of human MRE11A |
Buffer |
PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
Purification Method |
Affinity purification |
Dilution |
IHC 1:100-1:300 |
Conjugation |
Unconjugated |
Gene Accession |
NP_005582 |
Santa Cruz # |
sc-5859, sc-5858, sc-22767 |
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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.