Item no. |
E-AB-14487-200 |
Manufacturer |
Elabscience
|
Amount |
200uL |
Category |
|
Type |
Antibody Polyclonal |
Applications |
WB, ELISA |
Specific against |
Human, Mouse, Rat |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Activin A receptor type IIA, Activin receptor type 2A, Activin receptor type IIA, Activin receptor type-2A, ACTR 2, ACTR IIA, ACTR-IIA, ACTR2, ACTRII, ACTRIIA, Acvr 2, Acvr 2A, Acvr2, ACVR2A, AVR2A, OTTHUMP00000197918 |
Similar products |
ACTR-IIA, ACVR2A, ACTR2, Acvr2, Activin receptor type-2A, Activin receptor type IIA, ACTRII, OTTHUMP00000197918, AVR2A, ACTR IIA, Activin A receptor type IIA, Activin receptor type 2A, ACTR 2, ACTR 2, ACTRIIA, Acvr 2, Acvr 2A |
Available |
|
Research Areas |
Cancer, Metabolism, Signal Transduction, Stem Cells |
Synonyms |
Activin A receptor type IIA, Activin receptor type 2A, Activin receptor type IIA, Activin receptor type-2A, ACTR 2, ACTR IIA, ACTR-IIA, ACTR2, ACTRII, ACTRIIA, Acvr 2, Acvr 2A, Acvr2, ACVR2A, AVR2A, OTTHUMP00000197918 |
Swissprot |
P27037 |
Background |
This gene encodes activin A type II receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases. |
Concentration |
0.2 mg/mL |
Storage |
Store at -20C. Avoid freeze / thaw cycles. |
Immunogen |
Recombinant protein of human ACVR2A |
Buffer |
PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
Purification Method |
Affinity purification |
Dilution |
WB 1:500-1:2000 |
Conjugation |
Unconjugated |
Calculated MW |
58kDa |
Gene Accession |
BC069707 |
Santa Cruz # |
sc-5669, sc-130679, sc-25451 |
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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.