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PFN2 Polyclonal Antibody

PFN2 Polyclonal Antibody

Item no.	E-AB-12624-200
Manufacturer	Elabscience
Amount	200uL
Category	Neuroscience Aging & Neurological Disorders Antibodies Immunohistochemistry Western Blot ELISA Primary Antibodies
Type	Antibody Polyclonal
Applications	WB, IHC, ELISA
Specific against	Human, Mouse, Rat
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	D3S1319E, PFL, PFN 2, Pfn2, PROF2, Profilin II, Profilin-2, Profilin2, ProfilinII
Similar products	Profilin-2, Profilin II, PFL, Pfn2, D3S1319E, PFN 2, Profilin2, PROF2, ProfilinII
Available
Research Areas	Signal Transduction
Synonyms	D3S1319E, PFL, PFN 2, Pfn2, PROF2, Profilin II, Profilin-2, Profilin2, ProfilinII
Swissprot	P35080
Background	The protein encoded by this gene is a ubiquitous actin monomer-binding protein belonging to the profilin family. It is thought to regulate actin polymerization in response to extracellular signals. There are two alternatively spliced transcript variants encoding different isoforms described for this gene. Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG.
Concentration	0.3 mg/mL
Storage	Store at -20C. Avoid freeze / thaw cycles.
Immunogen	Synthetic peptide of human PFN2
Buffer	PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method	Affinity purification
Dilution	WB 1:500-1:2000, IHC 1:25-1:100
Conjugation	Unconjugated
Calculated MW	15kDa
Gene Accession	NP_444252

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 200uL

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Delivery expected until 9/6/2024

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