Item no. |
E-AB-10810-200 |
Manufacturer |
Elabscience
|
Amount |
200uL |
Category |
|
Type |
Antibody Polyclonal |
Applications |
IHC, ELISA |
Specific against |
Human, Mouse, Rat |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
2510006G12Rik, AA408751, AA536819, AA986414, ANAPC 5, ANAPC5, Anaphase promoting complex subunit 5, Anaphase-promoting complex subunit 5, Apc 5, APC5, APC5, Cyclosome subunit 5, PDL 108, PDL108, Periodontal ligament fibroblast protein, RMC1 |
Similar products |
APC5, ANAPC5, ANAPC 5, Anaphase promoting complex subunit 5, Anaphase-promoting complex subunit 5, Apc 5, Cyclosome subunit 5, PDL 108, PDL108, Periodontal ligament fibroblast protein, 2510006G12Rik, AA408751, AA536819, AA986414, RMC1 |
Available |
|
Research Areas |
Cell Biology |
Synonyms |
2510006G12Rik, AA408751, AA536819, AA986414, ANAPC 5, ANAPC5, Anaphase promoting complex subunit 5, Anaphase-promoting complex subunit 5, Apc 5, APC5, APC5, Cyclosome subunit 5, PDL 108, PDL108, Periodontal ligament fibroblast protein, RMC1 |
Swissprot |
Q9UJX4 |
Background |
This gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene. |
Concentration |
0.3 mg/mL |
Storage |
Store at -20C. Avoid freeze / thaw cycles. |
Immunogen |
Recombinant protein of human ANAPC5 |
Buffer |
PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
Purification Method |
Affinity purification |
Dilution |
IHC 1:50-1:200 |
Conjugation |
Unconjugated |
Gene Accession |
BC006301 |
Santa Cruz # |
sc-21417, sc-20986 |
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