APC5 Polyclonal Antibody

2510006G12Rik, AA408751, AA536819, AA986414, ANAPC 5, ANAPC5, Anaphase promoting complex subunit 5, Anaphase-promoting complex subunit 5, Apc 5, APC5, APC5, Cyclosome subunit 5, PDL 108, PDL108, Periodontal ligament fibroblast protein, RMC1

This gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene.

Store at -20C. Avoid freeze / thaw cycles.

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

IHC 1:50-1:200

BC006301