CPE Polyclonal Antibody

Carboxypeptidase E, Carboxypeptidase H, Carboxypeptidase H precursor, CarboxypeptidaseE, CarboxypeptidaseH, CBPE, Cobalt stimulated chromaffin granule carboxypeptidase, CPE, Cph 1, CPH, Enkephalin convertase, Entephalin convertase, Insulin granule associated carboxypeptidase, Prohormone processing carboxypeptidase, Prohormone-processing carboxypeptidase

This gene encodes a member of the M14 family of metallocarboxypeptidases. The encoded preproprotein is proteolytically processed to generate the mature peptidase. This peripheral membrane protein cleaves C-terminal amino acid residues and is involved in the biosynthesis of peptide hormones and neurotransmitters, including insulin. This protein may also function independently of its peptidase activity, as a neurotrophic factor that promotes neuronal survival, and as a sorting receptor that binds to regulated secretory pathway proteins, including prohormones. Mutations in this gene are implicated in type 2 diabetes.

Store at -20C. Avoid freeze / thaw cycles.

PBS with 0.02% sodium azide and 50% glycerol pH 7.4.

WB 1:500 - 1:2000 IF 1:50 - 1:200

49kDa/53kDa