Item no. |
E-AB-60939-200 |
Manufacturer |
Elabscience
|
Amount |
200uL |
Category |
|
Type |
Antibody Polyclonal |
Applications |
WB |
Specific against |
Human, Mouse |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
53 kDa BRG1 associated factor A, Actin like 6A, Actin like protein 6A, Actin related protein, Actin related protein Baf53a, actin-related protein 4, ACTL 6, ACTL 6A, ACTL6, ACTL6A, Arp4, ARPN BETA, ArpNbeta, BAF 53, BAF 53A, BAF complex 53 kDa subunit, BA |
Similar products |
ACTL6A, BAF53, INO80K, ArpNbeta, INO80 complex subunit K, ACTL6, Arp4, MGC5382, BAF complex 53 kDa subunit, actin-related protein 4, hArpN beta, 53 kDa BRG1 associated factor A, Actin like 6A, Actin like protein 6A, Actin related protein, Actin related protein Baf53a, ACTL 6, ACTL 6A, ARPN BETA, BAF 53, BAF 53A, BRG1 associated factor 53A, BRG1 associated factor, BRG1/brm associated factor 53A |
Available |
|
Research Areas |
Cancer, Epigenetics and Nuclear Signaling, Signal Transduction |
Synonyms |
53 kDa BRG1 associated factor A, Actin like 6A, Actin like protein 6A, Actin related protein, Actin related protein Baf53a, actin-related protein 4, ACTL 6, ACTL 6A, ACTL6, ACTL6A, Arp4, ARPN BETA, ArpNbeta, BAF 53, BAF 53A, BAF complex 53 kDa subunit, BAF53, BRG1 associated factor 53A, BRG1 associated factor, BRG1/brm associated factor 53A, hArpN beta, INO80 complex subunit K, INO80K, MGC5382 |
Swissprot |
O96019 |
Background |
This gene encodes a family member of actin-related proteins (ARPs), which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a 53 kDa subunit protein of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila; the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. Together with beta-actin, it is required for maximal ATPase activity of BRG1, and for the association of the BAF complex with chromatin/matrix. Three transcript variants that encode two different protein isoforms have been described. |
Concentration |
1 mg/mL |
Storage |
Store at -20C. Avoid freeze / thaw cycles. |
Immunogen |
Recombinant protein of human ACTL6A |
Buffer |
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. |
Purification Method |
Affinity purification |
Dilution |
WB 1:500 - 1:2000 |
Conjugation |
Unconjugated |
Calculated MW |
43kDa/47kDa |
Observed MW |
48kDa |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.