Item no. |
E-AB-60442-120 |
Manufacturer |
Elabscience
|
Amount |
120uL |
Category |
|
Type |
Antibody Polyclonal |
Applications |
WB |
Specific against |
Human, Mouse |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
HEM3, HMBS, Hydroxymethylbilane synthase, PBG D, PBG-D, PBGD, PORC, Porphobilinogen deaminase, porphyria, acute, Chester type, Pre uroporphyrinogen synthase, Pre-uroporphyrinogen synthase, UPS, Uroporphyrinogen I synthase, Uroporphyrinogen I synthetase |
Similar products |
HMBS, HEM3, PBG-D, PBGD, UPS, PORC, Hydroxymethylbilane synthase, PBG D, Porphobilinogen deaminase, Pre uroporphyrinogen synthase, Pre-uroporphyrinogen synthase, Uroporphyrinogen I synthase, porphyria, acute, Chester type, Uroporphyrinogen I synthetase |
Available |
|
Research Areas |
Cancer, Cell Biology, Metabolism, Signal Transduction |
Synonyms |
HEM3, HMBS, Hydroxymethylbilane synthase, PBG D, PBG-D, PBGD, PORC, Porphobilinogen deaminase, porphyria, acute, Chester type, Pre uroporphyrinogen synthase, Pre-uroporphyrinogen synthase, UPS, Uroporphyrinogen I synthase, Uroporphyrinogen I synthetase |
Swissprot |
P08397 |
Background |
This gene encodes a member of the hydroxymethylbilane synthase superfamily. The encoded protein is the third enzyme of the heme biosynthetic pathway and catalyzes the head to tail condensation of four porphobilinogen molecules into the linear hydroxymethylbilane. Mutations in this gene are associated with the autosomal dominant disease acute intermittent porphyria. Alternatively spliced transcript variants encoding different isoforms have been described. |
Concentration |
1 mg/mL |
Storage |
Store at -20C. Avoid freeze / thaw cycles. |
Immunogen |
Recombinant protein of human HMBS |
Buffer |
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. |
Purification Method |
Affinity purification |
Dilution |
WB 1:500 - 1:2000 |
Conjugation |
Unconjugated |
Calculated MW |
33kDa/34kDa/37kDa/39kDa |
Observed MW |
45kDa |
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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.