Item no. |
E-AB-60366-60 |
Manufacturer |
Elabscience
|
Amount |
60uL |
Category |
|
Type |
Antibody Polyclonal |
Applications |
WB |
Specific against |
Human, Mouse |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
DHFR, DHFRP1, Dihydrofolate reductase, DYR, DYR, EC 1.5.1.3 |
Similar products |
DHFR, Dihydrofolate reductase, DYR, DHFRP1, EC 1.5.1.3 |
Available |
|
Research Areas |
Cancer, Cell Biology, Metabolism, Signal Transduction |
Synonyms |
DHFR, DHFRP1, Dihydrofolate reductase, DYR, DYR, EC 1.5.1.3 |
Swissprot |
P00374 |
Background |
Dihydrofolate reductase converts dihydrofolate into tetrahydrofolate, a methyl group shuttle required for the de novo synthesis of purines, thymidylic acid, and certain amino acids. While the functional dihydrofolate reductase gene has been mapped to chromosome 5, multiple intronless processed pseudogenes or dihydrofolate reductase-like genes have been identified on separate chromosomes. Dihydrofolate reductase deficiency has been linked to megaloblastic anemia. Several transcript variants encoding different isoforms have been found for this gene. |
Concentration |
1 mg/mL |
Storage |
Store at -20C. Avoid freeze / thaw cycles. |
Immunogen |
Recombinant protein of human DHFR |
Buffer |
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. |
Purification Method |
Affinity purification |
Dilution |
WB 1:500 - 1:2000 |
Conjugation |
Unconjugated |
Calculated MW |
15kDa/21kDa |
Observed MW |
19kDa |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.