Item no. |
E-AB-60329-120 |
Manufacturer |
Elabscience
|
Amount |
120uL |
Category |
|
Type |
Antibody Polyclonal |
Applications |
WB |
Specific against |
Human, Mouse |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Mitochondrial uncoupling protein 3, SLC25A9, Solute carrier family 25 member 9, UCP 3, UCP3, UCP3, Uncoupling protein 3, Uncoupling protein 3 mitochondrial proton carrier |
Similar products |
UCP3, Mitochondrial uncoupling protein 3, UCP 3, Solute carrier family 25 member 9, SLC25A9, Uncoupling protein 3, Uncoupling protein 3 mitochondrial proton carrier |
Available |
|
Research Areas |
Cancer, Cardiovascular, Metabolism, Neuroscience, Signal Transduction |
Synonyms |
Mitochondrial uncoupling protein 3, SLC25A9, Solute carrier family 25 member 9, UCP 3, UCP3, UCP3, Uncoupling protein 3, Uncoupling protein 3 mitochondrial proton carrier |
Swissprot |
P55916 |
Background |
Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. The different UCPs have tissue-specific expression; this gene is primarily expressed in skeletal muscle. This gene's protein product is postulated to protect mitochondria against lipid-induced oxidative stress. Expression levels of this gene increase when fatty acid supplies to mitochondria exceed their oxidation capacity and the protein enables the export of fatty acids from mitochondria. UCPs contain the three solcar protein domains typically found in MACPs. Two splice variants have been found for this gene. |
Concentration |
1 mg/mL |
Storage |
Store at -20C. Avoid freeze / thaw cycles. |
Immunogen |
Recombinant protein of human UCP3 |
Buffer |
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. |
Purification Method |
Affinity purification |
Dilution |
WB 1:500 - 1:2000 |
Conjugation |
Unconjugated |
Calculated MW |
22kDa/29kDa/34kDa |
Observed MW |
25kDa |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.