Item no. |
E-AB-60298-200 |
Manufacturer |
Elabscience
|
Amount |
200uL |
Category |
|
Type |
Antibody Polyclonal |
Applications |
WB |
Specific against |
Human, Mouse |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
20 lyase, CP17A, CPT7, CYP17, CYP17A1, CYPXVII, Cytochrome P450 17A1, Cytochrome P450 family 17, Cytochrome P450 family 17 subfamily A polypeptide 1, Cytochrome p450 subfamily XVII (steroid 17 alpha hydroxylase) adrenal hyperplasia, Cytochrome p450 XVIIA1 |
Similar products |
CYP17A1, CYP17, Cytochrome P450 17A1, S17AH, CPT7, 20 lyase, CYPXVII, Cytochrome P450 family 17, Cytochrome P450 family 17 subfamily A polypeptide 1, Cytochrome p450 XVIIA1, P450 C17, P450c17, Steroid 17 alpha hydroxylase/17, Steroid 17 alpha monooxygenase, Steroid 17-alpha-hydroxylase/17, Cytochrome P450-C17, Cytochrome P450c17, Steroid 17-alpha-monooxygenase, CP17A, Cytochrome p450 subfamily XVII (steroid 17 alpha hydroxylase) adrenal hyperplasia, OTTHUMP00000020382 |
Available |
|
Research Areas |
Cancer, Cardiovascular, Metabolism, Signal Transduction |
Synonyms |
20 lyase, CP17A, CPT7, CYP17, CYP17A1, CYPXVII, Cytochrome P450 17A1, Cytochrome P450 family 17, Cytochrome P450 family 17 subfamily A polypeptide 1, Cytochrome p450 subfamily XVII (steroid 17 alpha hydroxylase) adrenal hyperplasia, Cytochrome p450 XVIIA1, Cytochrome P450-C17, Cytochrome P450c17, OTTHUMP00000020382, P450 C17, P450c17, S17AH, Steroid 17 alpha hydroxylase/17, 20 lyase, Steroid 17 alpha monooxygenase, Steroid 17-alpha-hydroxylase/17, Steroid 17-alpha-monooxygenase |
Swissprot |
P05093 |
Background |
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. It has both 17alpha-hydroxylase and 17, 20-lyase activities and is a key enzyme in the steroidogenic pathway that produces progestins, mineralocorticoids, glucocorticoids, androgens, and estrogens. Mutations in this gene are associated with isolated steroid-17 alpha-hydroxylase deficiency, 17-alpha-hydroxylase/17, 20-lyase deficiency, pseudohermaphroditism, and adrenal hyperplasia. |
Concentration |
1 mg/mL |
Storage |
Store at -20C. Avoid freeze / thaw cycles. |
Immunogen |
Recombinant protein of human CYP17A1 |
Buffer |
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. |
Purification Method |
Affinity purification |
Dilution |
WB 1:500 - 1:2000 |
Conjugation |
Unconjugated |
Calculated MW |
57kDa |
Observed MW |
50kDa |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.