TSTA3 Polyclonal Antibody

3 5 epimerase/4 reductase, 5-epimerase-4-reductase, anti TSTA3, EC 1.1.1.271, FCL, FX, GDP 4 keto 6 deoxy D mannose 3 5 epimerase 4 reductase, GDP 4 keto 6 deoxy D mannose epimerase reductase, GDP L fucose synthase, GDP-4-keto-6-deoxy-D-mannose-3, GDP-L-fucose synthase, P35B, Protein FX, Red cell NADP(H) binding protein, Red cell NADP(H)-binding protein, SDR4E1, Short chain dehydrogenase/reductase family 4E member 1, Short-chain dehydrogenase/reductase family 4E member 1, Tissue specific transplantation antigen 3, Tissue specific transplantation antigen P35B, TSTA3, TSTA3

Tissue specific transplantation antigen P35B is a NADP(H)-binding protein. It catalyze the two-step epimerase and the reductase reactions in GDP-D-mannose metabolism, converting GDP-4-keto-6-D-deoxymannose to GDP-L-fucose. GDP-L-fucose is the substrate of several fucosyltransferases involved in the expression of many glycoconjugates, including blood group ABH antigens and developmental adhesion antigens. Mutations in this gene may cause leukocyte adhesion deficiency, type II.

Store at -20C. Avoid freeze / thaw cycles.

PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

IHC 1:50-1:200, ELISA 1:5000-1:10000

BC001941