ZBTB5 Polyclonal Antibody

5930421I10, 9430083K24Rik, AI646847, Expressed in brain and neural tube, KIAA0354, mKIAA0354, OTTMUSP00000007812, OTTMUSP00000007813, OTTMUSP00000007814, RP11-397D12.5, RP23-218A4.2, Transcription factor ZNF POZ, Zbtb5, ZBTB5, Zinc finger and BTB domain containing protein 5, Zinc finger and BTB domain-containing protein 5

Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. Zinc finger and BTB domain-containing protein 5 (ZBTB5) is a 677 amino acid member of the Krüppel C2H2-type zinc-finger protein family. Localized to the nucleus, ZBTB5 contains a BTB domain, also known as a POZ domain, which inhibits DNA binding and mediates homotypic and heterotypic dimerization. Characteristics of the BTB domain suggest that ZBTB5 functions as a transcription regulator.

Store at -20C. Avoid freeze / thaw cycles.

PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

WB 1:500-1:2000, ELISA 1:5000-1:10000

74 kDa

BC010007