Item no. |
E-AB-19682-60 |
Manufacturer |
Elabscience
|
Amount |
60uL |
Category |
|
Type |
Antibody Polyclonal |
Applications |
IHC, ELISA |
Specific against |
Human, Mouse |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 5.1 |
32160702 |
ECLASS 6.1 |
32160702 |
ECLASS 8.0 |
32160702 |
ECLASS 9.0 |
32160702 |
ECLASS 10.0.1 |
32160702 |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Br cadherin, BR-cadherin, Brain cadherin, CAD12_HUMAN, cadherin 12 (N cadherin 2), Cadherin 12, Cadherin 12 precursor, Cadherin 12 type 2 (N cadherin 2), Cadherin 12 type 2, Cadherin neural type 2, Cadherin-12, CDH12, CDHB, FLJ34857, N cadherin 2, N-cadhe |
Similar products |
CDH12, CDHB, FLJ34857, N-cadherin 2, Cadherin-12, Br cadherin, BR-cadherin, Brain cadherin, CAD12_HUMAN, Cadherin 12, Cadherin 12 precursor, Cadherin 12 type 2, Cadherin neural type 2, N cadherin 2, Neural type cadherin 2, Neuronal cadherin 2, cadherin 12 (N cadherin 2), Cadherin 12 type 2 (N cadherin 2) |
Available |
|
Research Areas |
Signal Transduction |
Synonyms |
Br cadherin, BR-cadherin, Brain cadherin, CAD12_HUMAN, cadherin 12 (N cadherin 2), Cadherin 12, Cadherin 12 precursor, Cadherin 12 type 2 (N cadherin 2), Cadherin 12 type 2, Cadherin neural type 2, Cadherin-12, CDH12, CDHB, FLJ34857, N cadherin 2, N-cadherin 2, Neural type cadherin 2, Neuronal cadherin 2 |
Swissprot |
P55289 |
Background |
This gene encodes a type II classical cadherin of the cadherin superfamily. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature cadherin protein. These integral membrane proteins mediate calcium-dependent cell-cell adhesion and are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a histidine-alanine-valine (HAV) cell adhesion recognition sequence specific to type I cadherins. This particular cadherin appears to be expressed specifically in the brain and its temporal pattern of expression would be consistent with a role during a critical period of neuronal development, perhaps specifically during synaptogenesis. |
Concentration |
1.74 mg/mL |
Storage |
Store at -20C. Avoid freeze / thaw cycles. |
Immunogen |
Synthetic peptide of human CDH12 |
Buffer |
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4 |
Purification Method |
Antigen affinity purification |
Dilution |
IHC 1:50-1:100, ELISA 1:5000-1:10000 |
Conjugation |
Unconjugated |
Gene Accession |
NP004052 |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.