Item no. |
E-AB-18486-60 |
Manufacturer |
Elabscience
|
Amount |
60uL |
Category |
|
Type |
Antibody Polyclonal |
Applications |
WB, IHC, ELISA |
Specific against |
Human, Mouse |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
PROF, Propeller-FYVE protein, RP11 147H23.1, WD repeat and FYVE domain containing 2, WD repeat and FYVE domain-containing protein 2, WD40 and FYVE domain containing 2, WD40- and FYVE domain-containing protein 2, WDF2, Wdfy2, WDFY2, ZFYVE22, Zinc finger FY |
Similar products |
Wdfy2, WDFY2, PROF, WDF2, ZFYVE22, WD40 and FYVE domain containing 2, WD repeat and FYVE domain-containing protein 2, Propeller-FYVE protein, RP11 147H23.1, WD repeat and FYVE domain containing 2, WD40- and FYVE domain-containing protein 2, Zinc finger FYVE domain-containing protein 22 |
Available |
|
Research Areas |
Signal transduction |
Synonyms |
PROF, Propeller-FYVE protein, RP11 147H23.1, WD repeat and FYVE domain containing 2, WD repeat and FYVE domain-containing protein 2, WD40 and FYVE domain containing 2, WD40- and FYVE domain-containing protein 2, WDF2, Wdfy2, WDFY2, ZFYVE22, Zinc finger FYVE domain-containing protein 22 |
Swissprot |
Q96P53 |
Background |
WD repeat and FYVE domain-containing protein 2 (WDFY2), also known as WDF2 and ZFYVE22, is a 400 amino acid protein that localizes to a set of small endosomes that are found within 100 nm from the plasma membrane. Highly conserved between species, WDFY2 consists of one FYVE-type zinc finger and seven WD repeats. The FYVE domain is a cysteine-rich domain of about 70 amino acids. Its primary role is to target signal-transducing proteins to cell membranes through binding to the membrane lipid phosphatidylinositol-3-phosphate with high specificity. WD-repeats are generally found in clusters of seven. They have no intrinsic catalytic activity, but they serve as a platform for protein-protein interactions. WDFY2 is suspected to play a critical role in the endocytic pathway. |
Concentration |
0.6 mg/mL |
Storage |
Store at -20C. Avoid freeze / thaw cycles. |
Immunogen |
Fusion protein of human WDFY2 |
Buffer |
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4 |
Purification Method |
Antigen affinity purification |
Dilution |
WB 1:500-1:2000, IHC 1:30-1:150, ELISA 1:5000-1:10000 |
Conjugation |
Unconjugated |
Calculated MW |
45 kDa |
Observed MW |
Refer to figures |
Gene Accession |
BC014004 |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.