Item no. |
E-AB-15735-120 |
Manufacturer |
Elabscience
|
Amount |
120uL |
Category |
|
Type |
Antibody Polyclonal |
Applications |
WB, IHC, ELISA |
Specific against |
Human, Mouse, Rat |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
c Jun kinase 2, C Jun N terminal kinase 2, c-Jun N-terminal kinase 2, JNK 55, JNK-55, JNK2 alpha, JNK2, JNK2 beta, JNK2A, JNK2alpha, JNK2B, JNK2BETA, Jun kinase, MAP kinase 9, MAPK 9, Mapk9, Mitogen activated protein kinase 9, Mitogen-activated protein ki |
Similar products |
JNK2, Mapk9, Mitogen-activated protein kinase 9, Stress-activated protein kinase JNK2, c-Jun N-terminal kinase 2, 9, mitogen-activated, JNK-55, JNK2A, JNK2B, JNK2BETA, PRKM9, SAPK, p54aSAPK, Jun kinase, MAP kinase 9, MK09, SAPK1a, MAPK 9, C Jun N terminal kinase 2, JNK 55, JNK2 alpha, JNK2 beta, JNK2alpha, Mitogen activated protein kinase 9, SAPK alpha, Protein kinase, Stress activated protein kinase 1a, c Jun kinase 2, P54a |
Available |
|
Research Areas |
Cancer, Cell Biology, Metabolism, Immunology, Signal Transduction |
Synonyms |
c Jun kinase 2, C Jun N terminal kinase 2, c-Jun N-terminal kinase 2, JNK 55, JNK-55, JNK2 alpha, JNK2, JNK2 beta, JNK2A, JNK2alpha, JNK2B, JNK2BETA, Jun kinase, MAP kinase 9, MAPK 9, Mapk9, Mitogen activated protein kinase 9, Mitogen-activated protein kinase 9, MK09, P54a, p54aSAPK, PRKM9, Protein kinase, mitogen-activated, 9, SAPK alpha, SAPK, SAPK1a, Stress activated protein kinase 1a, Stress-activated protein kinase JNK2 |
Swissprot |
P45984 |
Background |
Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, primarily components of AP-1 such as c-Jun and ATF2 and thus regulates AP-1 transcriptional activity. In T-cells, JNK1 and JNK2 are required for polarized differentiation of T-helper cells into Th1 cells.JNK2 isoforms display different binding patterns: alpha-1 and alpha-2 preferentially bind to c-Jun, whereas beta-1 and beta-2 bind to ATF2. However, there is no correlation between binding and phosphorylation, which is achieved at about the same efficiency by all isoforms. JUNB is not a substrate for JNK2 alpha-2, and JUND binds only weakly to it. |
Concentration |
0.4 mg/mL |
Storage |
Store at -20C. Avoid freeze / thaw cycles. |
Immunogen |
Synthetic peptide of human MAPK9 |
Buffer |
PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
Purification Method |
Affinity purification |
Dilution |
WB 1:500-1:2000, IHC 1:25-1:100 |
Conjugation |
Unconjugated |
Calculated MW |
48kDa |
Observed MW |
Refer to figures |
Gene Accession |
NP_620707 |
Santa Cruz # |
sc-46013, sc-46011, sc-827, sc-572 |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.