Item no. |
E-AB-11474-60 |
Manufacturer |
Elabscience
|
Amount |
60uL |
Category |
|
Type |
Antibody Polyclonal |
Applications |
IHC, ELISA |
Specific against |
Human, Mouse |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
5330431N24Rik, AI851877, C12orf6, DKFZp779H0122, HIN1L, MIB006, OTTMUSP00000027219, Poly (ADP ribose) polymerase family member 11, RGD1561791 |
Similar products |
HIN1L, MIB006, C12orf6, 5330431N24Rik, AI851877, DKFZp779H0122, OTTMUSP00000027219, Poly (ADP ribose) polymerase family member 11, RGD1561791 |
Available |
|
Research Areas |
Epigenetics and Nuclear Signaling |
Synonyms |
5330431N24Rik, AI851877, C12orf6, DKFZp779H0122, HIN1L, MIB006, OTTMUSP00000027219, Poly (ADP ribose) polymerase family member 11, RGD1561791 |
Swissprot |
Q9NR21 |
Background |
Poly(ADP-ribosylation) is a method of DNA damage-dependent posttranslational modification that helps to rescue injured proliferating cells from cell death. The PARP (poly(ADP-ribose) polymerase) proteins comprise a superfamily of enzymes that functionally modify histones and other nuclear proteins, thereby preventing cell death. PARPs use NAD+ as a substrate to catalytically transfer ADP-ribose residues onto protein acceptors; a process that, when repeated multiple times, leads to the formation of poly(ADPribose) chains on the protein. |
Concentration |
0.4 mg/mL |
Storage |
Store at -20C. Avoid freeze / thaw cycles. |
Immunogen |
Recombinant protein of human PARP11 |
Buffer |
PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
Purification Method |
Affinity purification |
Dilution |
IHC 1:50-1:200 |
Conjugation |
Unconjugated |
Gene Accession |
BC017569 |
Santa Cruz # |
sc-82967, sc-82968, sc-130836 |
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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.