Comparison

AF/LE Purified Anti-Human CD274/PD-L1 Monoclonal Antibody[29E.2A3]

Item no. E-AB-F11330-50
Manufacturer Elabscience
Amount 50ug
Category
Type Antibody Monoclonal
Applications FC, IHC, Functional Assays
Clone 29E.2A3
Specific against Human (Homo sapiens)
Host Mouse
Isotype IgG2b kappa
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias B7-H1, PD-L1, Programmed cell death ligand 1, B7 homolog 1, B7-H, B7H1, PDL1, PDCD1L1, PDCD1LG1
Similar products B7H1, PDCD1L1, PDCD1LG1, PDL1, B7 homolog 1, PD-L1, B7-H, B7-H1, Programmed cell death ligand 1
Available
Synonyms
B7-H1, PD-L1, Programmed cell death ligand 1, B7 homolog 1, B7-H, B7H1, PDL1, PDCD1L1, PDCD1LG1
Swissprot
Q9NZQ7
Background
CD274, also known as PD-L1 and B7-H1, is type I transmembrane glycoprotein that serves as a ligand for CD279 (PD-1). This interaction is believed to regulate the balance between the stimulatory and inhibitory signals needed for responses to microbes and maintenance of self-tolerance. CD274 is involved in the costimulation of T cell proliferation and IL-10 and IFN-gamma production in an IL-2-dependent and CD279-independent manner. Conflicting data has shown that CD274 can inhibit T cell proliferation and cytokine production, and alternatively, enhance T cell activation. Other studies suggest that CD274 may signal bidirectionally, raising interesting implications for its expression in a wide variety of cell types, including T and B cells, antigen-presenting cells, and nonhematopoietic cells.
Concentration
0.5 mg/mL
Storage
Store at 2ca.8C. Do not freeze.
Buffer
0.2 um filtered in PBS, pH7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.
Conjugation
None (Purified antibody-Azide Free/Low endotoxin)

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 50ug
Available: In stock
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