Item no. |
E-AB-64739-200 |
Manufacturer |
Elabscience
|
Amount |
200uL |
Category |
|
Type |
Antibody Polyclonal |
Applications |
IF |
Specific against |
Human |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
CD177, CD177 antigen, CD177 molecule, CD177, HNA-2a, HNA2A, Human neutrophil alloantigen 2a, NB1, NB1 glycoprotein, NB1 GP, Polycythemia rubra vera 1, Polycythemia rubra vera protein 1, PRV-1, PRV1 |
Similar products |
CD177, HNA2A, NB1, PRV1, CD177 antigen, PRV-1, HNA-2a, NB1 GP, NB1 glycoprotein, Polycythemia rubra vera protein 1, NB1 glycoprotein, Human neutrophil alloantigen 2a, CD177 molecule, Polycythemia rubra vera 1 |
Available |
|
Research Areas |
Immunology |
Synonyms |
CD177, CD177 antigen, CD177 molecule, CD177, HNA-2a, HNA2A, Human neutrophil alloantigen 2a, NB1, NB1 glycoprotein, NB1 GP, Polycythemia rubra vera 1, Polycythemia rubra vera protein 1, PRV-1, PRV1 |
Swissprot |
Q8N6Q3 |
Background |
This gene encodes a glycosyl-phosphatidylinositol (GPI)-linked cell surface glycoprotein that plays a role in neutrophil activation. The protein can bind platelet endothelial cell adhesion molecule-1 and function in neutrophil transmigration. Mutations in this gene are associated with myeloproliferative diseases. Over-expression of this gene has been found in patients with polycythemia rubra vera. Autoantibodies against the protein may result in pulmonary transfusion reactions, and it may be involved in Wegener's granulomatosis. A related pseudogene, which is adjacent to this gene on chromosome 19, has been identified. |
Concentration |
1 mg/mL |
Storage |
Store at -20C. Avoid freeze / thaw cycles. |
Immunogen |
Recombinant protein of human CD177 |
Buffer |
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. |
Purification Method |
Affinity purification |
Dilution |
IF 1:50 - 1:200 |
Conjugation |
Unconjugated |
Calculated MW |
15kDa/27kDa/46kDa |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.