Alias |
Anhidrotic ectodysplasin receptor 1, DL, Downless (mouse) homolog, Downless homolog, Downless mouse homolog of, ECTD10A, ECTD10B, Ectodermal dysplasia receptor, Ectodysplasin 1 anhidrotic receptor, Ectodysplasin A receptor, Ectodysplasin A1 isoform recept |
Similar products |
EDAR, DL, ED1R, ED3, ED5, EDA1R, EDA3, HRM1, Edar, Anhidrotic ectodysplasin receptor 1, Downless homolog, Downless mouse homolog of, Ectodermal dysplasia receptor, Ectodysplasin 1 anhidrotic receptor, Ectodysplasin A receptor, Ectodysplasin-A receptor, ED 1R, ED 3, ED 5, EDA 1R, EDA 3, EDA A1 receptor, EDA A1R, EDA-A1 receptor, Tumor necrosis factor receptor superfamily member EDAR, Downless (mouse) homolog, ECTD10A, ECTD10B, Ectodysplasin A1 isoform receptor |
Synonyms |
Anhidrotic ectodysplasin receptor 1, DL, Downless (mouse) homolog, Downless homolog, Downless mouse homolog of, ECTD10A, ECTD10B, Ectodermal dysplasia receptor, Ectodysplasin 1 anhidrotic receptor, Ectodysplasin A receptor, Ectodysplasin A1 isoform receptor, Ectodysplasin-A receptor, ED 1R, ED 3, ED 5, ED1R, ED3, ED5, EDA 1R, EDA 3, EDA A1 receptor, EDA A1R, EDA-A1 receptor, EDA1R, EDA3, Edar, EDAR, HRM1, Tumor necrosis factor receptor superfamily member EDAR |
Background |
This gene encodes a member of the tumor necrosis factor receptor family. The encoded transmembrane protein is a receptor for the soluble ligand ectodysplasin A, and can activate the nuclear factor-kappaB, JNK, and caspase-independent cell death pathways. It is required for the development of hair, teeth, and other ectodermal derivatives. Mutations in this gene result in autosomal dominant and recessive forms of hypohidrotic ectodermal dysplasia. |