Item no. |
E-AB-62147-120 |
Manufacturer |
Elabscience
|
Amount |
120uL |
Category |
|
Type |
Antibody Polyclonal |
Applications |
WB, IHC |
Specific against |
Human |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Cell proliferation-inducing gene 53 protein, E3 ubiquitin protein ligase Nedd4, E3 ubiquitin-protein ligase NEDD4, HECT-type E3 ubiquitin transferase NEDD4, KIAA0093, NEDD 4, NEDD-4, Nedd4, NEDD4, Neural precursor cell expressed developmentally down regul |
Similar products |
NEDD4, RPF1, E3 ubiquitin protein ligase, Nedd4, neural precursor cell expressed, KIAA0093, receptor-potentiating factor 1, E3 ubiquitin-protein ligase NEDD4, Cell proliferation-inducing gene 53 protein, Neural precursor cell expressed developmentally down-regulated protein 4, NEDD-4, PIG53, E3 ubiquitin protein ligase Nedd4, HECT-type E3 ubiquitin transferase NEDD4, NEDD 4, Neural precursor cell expressed developmentally down regulated 4, developmentally down-regulated 4 |
Available |
|
Research Areas |
Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Neuroscience |
Synonyms |
Cell proliferation-inducing gene 53 protein, E3 ubiquitin protein ligase Nedd4, E3 ubiquitin-protein ligase NEDD4, HECT-type E3 ubiquitin transferase NEDD4, KIAA0093, NEDD 4, NEDD-4, Nedd4, NEDD4, Neural precursor cell expressed developmentally down regulated 4, Neural precursor cell expressed developmentally down-regulated protein 4, neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase, PIG53, receptor-potentiating factor 1, RPF1 |
Swissprot |
P46934 |
Background |
This gene is the founding member of the NEDD4 family of HECT ubiquitin ligases that function in the ubiquitin proteasome system of protein degradation. The encoded protein contains an N-terminal calcium and phospholipid binding C2 domain followed by multiple tryptophan-rich WW domains and, a C-terminal HECT ubiquitin ligase catalytic domain. It plays critical role in the regulation of a number of membrane receptors, endocytic machinery components and the tumor suppressor PTEN. |
Concentration |
1 mg/mL |
Storage |
Store at -20C. Avoid freeze / thaw cycles. |
Immunogen |
Recombinant protein of human NEDD4 |
Buffer |
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. |
Purification Method |
Affinity purification |
Dilution |
WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
Conjugation |
Unconjugated |
Calculated MW |
104kDa/140kDa/147kDa/149kDa |
Observed MW |
120kDa |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.