Item no. |
E-AB-61490-60 |
Manufacturer |
Elabscience
|
Amount |
60uL |
Category |
|
Type |
Antibody Polyclonal |
Applications |
WB, IF |
Specific against |
Human |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
hN CoR, hNCoR, KIAA1047, N CoR, N Cor/SMRT corepressor Rip13, N CoR1, N-CoR, N-CoR1, NCOR 1, NCoR, Ncor1, NCOR1, Nuclear receptor co repressor 1, Nuclear receptor corepressor 1, Retinoid X receptor interacting protein 13, RIP13, Rxrip13, thyroid hormone a |
Similar products |
NCOR1, KIAA1047, Nuclear receptor corepressor 1, N-CoR, TRAC1, Ncor1, RIP13, Rxrip13, hN CoR, hNCoR, N CoR, N Cor/SMRT corepressor Rip13, N CoR1, NCOR 1, NCoR, Nuclear receptor co repressor 1, Retinoid X receptor interacting protein 13, thyroid hormone and retinoic acid receptor associated corepressor 1, TRAC 1, N-CoR1 |
Available |
|
Research Areas |
Cancer, Epigenetics and Nuclear Signaling, Metabolism, Signal Transduction |
Synonyms |
hN CoR, hNCoR, KIAA1047, N CoR, N Cor/SMRT corepressor Rip13, N CoR1, N-CoR, N-CoR1, NCOR 1, NCoR, Ncor1, NCOR1, Nuclear receptor co repressor 1, Nuclear receptor corepressor 1, Retinoid X receptor interacting protein 13, RIP13, Rxrip13, thyroid hormone and retinoic acid receptor associated corepressor 1, TRAC 1, TRAC1 |
Swissprot |
O75376 |
Background |
This gene encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. This gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 17 and 20. |
Concentration |
1 mg/mL |
Storage |
Store at -20C. Avoid freeze / thaw cycles. |
Immunogen |
Recombinant protein of human NCOR1 |
Buffer |
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. |
Purification Method |
Affinity purification |
Dilution |
WB 1:500 - 1:2000 IF 1:50 - 1:100 |
Conjugation |
Unconjugated |
Calculated MW |
103kDa/258kDa/270kDa |
Observed MW |
320kDa |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.