Item no. |
E-AB-52700-200 |
Manufacturer |
Elabscience
|
Amount |
200uL |
Category |
|
Type |
Antibody Polyclonal |
Applications |
IHC, ELISA |
Specific against |
Human |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
2310020H20Rik, HML, hnifU, Iron sulfur cluster assembly enzyme ISCU mitochondrial, Iron sulfur cluster scaffold homolog (E. coli), Iron sulfur cluster scaffold homolog, Iron-sulfur cluster assembly enzyme ISCU, Iscu, IscU iron sulfur cluster scaffold homo |
Similar products |
ISCU, Iscu, mitochondrial, NIFUN, Iron-sulfur cluster assembly enzyme ISCU, NifU-like N-terminal domain-containing protein, NifU-like protein, ISU2, HML, 2310020H20Rik, MGC74517, NIFU, hnifU, Iron sulfur cluster assembly enzyme ISCU mitochondrial, Iron sulfur cluster scaffold homolog (E. coli), Iron sulfur cluster scaffold homolog, IscU iron sulfur cluster scaffold homolog, NifU like N terminal domain containing, NifU like N terminal domain containing protein, NifU like protein, Nitrogen fixation cluster like, OTTHUMP00000238760, OTTHUMP00000238761, OTTHUMP00000238762, OTTHUMP00000238764, OTTHUMP00000238765 |
Available |
|
Research Areas |
Metabolism, Signal transduction |
Synonyms |
2310020H20Rik, HML, hnifU, Iron sulfur cluster assembly enzyme ISCU mitochondrial, Iron sulfur cluster scaffold homolog (E. coli), Iron sulfur cluster scaffold homolog, Iron-sulfur cluster assembly enzyme ISCU, Iscu, IscU iron sulfur cluster scaffold homolog, ISCU, ISU2, MGC74517, mitochondrial, NIFU, NifU like N terminal domain containing, NifU like N terminal domain containing protein, NifU like protein, NifU-like N-terminal domain-containing protein, NifU-like protein, NIFUN, Nitrogen fixation cluster like, OTTHUMP00000238760, OTTHUMP00000238761, OTTHUMP00000238762, OTTHUMP00000238764, OTTHUMP00000238765 |
Swissprot |
Q9H1K1 |
Background |
This gene encodes a component of the iron-sulfur (Fe-S) cluster scaffold. Fe-S clusters are cofactors that play a role in the function of a diverse set of enzymes, including those that regulate metabolism, iron homeostasis, and oxidative stress response. Alternative splicing results in transcript variants encoding different protein isoforms that localize either to the cytosol or to the mitochondrion. Mutations in this gene have been found in patients with hereditary myopathy with lactic acidosis. A disease-associated mutation in an intron may activate a cryptic splice site, resulting in the production of a splice variant encoding a putatively non-functional protein. A pseudogene of this gene is present on chromosome 1. |
Concentration |
0.78 mg/mL |
Storage |
Store at -20C. Avoid freeze / thaw cycles. |
Immunogen |
Fusion protein of human ISCU |
Buffer |
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4 |
Purification Method |
Antigen affinity purification |
Dilution |
IHC 1:40-1:200, ELISA 1:5000-1:10000 |
Conjugation |
Unconjugated |
Gene Accession |
BC011906 |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.