Item no. |
E-AB-52192-60 |
Manufacturer |
Elabscience
|
Amount |
60uL |
Category |
|
Type |
Antibody Polyclonal |
Applications |
IHC, ELISA |
Specific against |
Human |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
11 beta HSD 1, 11 beta HSD1, 11 beta hydroxysteroid dehydrogenase 1, 11 DH, 11-beta hydroxysteroid dehydrogenase, type 1, 11-beta-HSD1, 11-beta-hydroxysteroid dehydrogenase 1, 11-DH, 11DH, Corticosteroid 11 beta dehydrogenase isozyme 1, Corticosteroid 11- |
Similar products |
HDL, HSD11B1, member 1, HSD11, type 1, 11-DH, 11-beta-HSD1, HSD11B, HSD11L, MGC13539, SDR26C1, 11-beta-hydroxysteroid dehydrogenase 1, CORTRD2, Corticosteroid 11-beta-dehydrogenase isozyme 1, 11-beta hydroxysteroid dehydrogenase, short chain dehydrogenase/reductase family 26C, 11DH, 11 beta HSD 1, 11 beta HSD1, 11 beta hydroxysteroid dehydrogenase 1, 11 DH, Corticosteroid 11 beta dehydrogenase isozyme 1, DHI1, HSD 11, Hydroxysteroid (11 beta) dehydrogenase, Hydroxysteroid (11 beta) dehydrogenase 1 |
Available |
|
Research Areas |
Cancer, Metabolism, Signal Transduction |
Synonyms |
11 beta HSD 1, 11 beta HSD1, 11 beta hydroxysteroid dehydrogenase 1, 11 DH, 11-beta hydroxysteroid dehydrogenase, type 1, 11-beta-HSD1, 11-beta-hydroxysteroid dehydrogenase 1, 11-DH, 11DH, Corticosteroid 11 beta dehydrogenase isozyme 1, Corticosteroid 11-beta-dehydrogenase isozyme 1, CORTRD2, DHI1, HDL, HSD 11, HSD11, HSD11B, HSD11B1, HSD11L, Hydroxysteroid (11 beta) dehydrogenase, Hydroxysteroid (11 beta) dehydrogenase 1, MGC13539, SDR26C1, short chain dehydrogenase/reductase family 26C, member 1 |
Swissprot |
P28845 |
Background |
The protein encoded by this gene is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, the encoded protein can catalyze the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in this gene has been associated with obesity and insulin resistance in children. Mutations in this gene and H6PD (hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)) are the cause of cortisone reductase deficiency. Alternate splicing results in multiple transcript variants encoding the same protein. |
Concentration |
1.2 mg/mL |
Storage |
Store at -20C. Avoid freeze / thaw cycles. |
Immunogen |
Fusion protein of human HSD11B1 |
Buffer |
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4 |
Purification Method |
Antigen affinity purification |
Dilution |
IHC 1:50-1:200, ELISA 1:5000-1:10000 |
Conjugation |
Unconjugated |
Gene Accession |
BC012593 |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.