KLF1 Polyclonal Antibody

CDAN4, EKLF, EKLF PEN, Erythroid krueppel like transcription factor (EKLF) (Erythroid transcription factor), Erythroid krueppel-like transcription factor, Erythroid Kruppel like factor, Erythroid specific transcription factor EKLF, HBFQTL6, Human erythroid-specific transcription factor EKLF mRNA complete cds, INLU, Klf1, KLF1, Krueppel-like factor 1, Kruppel like factor 1 (erythroid)

This gene encodes a hematopoietic-specific transcription factor that induces high-level expression of adult beta-globin and other erythroid genes. The zinc-finger protein binds to the DNA sequence CCACACCCT found in the beta hemoglobin promoter. Heterozygous loss-of-function mutations in this gene result in the dominant In(Lu) blood phenotype.KLF1 (Kruppel Like Factor 1) is a Protein Coding gene. Diseases associated with KLF1 include Dyserythropoietic Anemia, Congenital, Type Iv and Hereditary Persistence Of Fetal Hemoglobin-Sickle Cell Disease Syndrome. Among its related pathways are Hematopoietic Stem Cell Differentiation. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and core promoter proximal region sequence-specific DNA binding. An important paralog of this gene is KLF4.

Store at -20C. Avoid freeze / thaw cycles.

PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4

WB 1:500-1:2000, ELISA 1:20000

38kDa