Item no. |
E-AB-19551-60 |
Manufacturer |
Elabscience
|
Amount |
60uL |
Category |
|
Type |
Antibody Polyclonal |
Applications |
WB, IHC, ELISA |
Specific against |
Human |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
FLJ12752, OTTHUMP00000207119, RINZF, RINZFC, ZBT10, ZBTB10, Zinc finger and BTB domain containing protein 10, Zinc finger and BTB domain-containing protein 10, Zinc finger protein RIN ZF |
Similar products |
ZBTB10, FLJ12752, RINZF, OTTHUMP00000207119, ZBT10, Zinc finger and BTB domain-containing protein 10, RINZFC, Zinc finger and BTB domain containing protein 10, Zinc finger protein RIN ZF |
Available |
|
Research Areas |
Epigenetics and Nuclear Signaling |
Synonyms |
FLJ12752, OTTHUMP00000207119, RINZF, RINZFC, ZBT10, ZBTB10, Zinc finger and BTB domain containing protein 10, Zinc finger and BTB domain-containing protein 10, Zinc finger protein RIN ZF |
Swissprot |
Q96DT7 |
Background |
RINZF, also known as ZBTB10 (zinc finger and BTB domain containing protein 10), is a 847 amino acid protein that contains one BTB/POZ domain and two C2H2-type zinc fingers. Localized to the nucleus, RINZF is believed to play a role in transcriptional regulation. Specifically, RINZF is capable of binding to the CACC element of the Gastrin promoter. In this regard, RINZF competes with Sp1 for CACC binding and interferes with Sp1 transactivation, thereby regulating Gastrin gene expression. The rat RINZF protein shares 98% homology with the human RINZF protein, suggesting that RINZF is a conserved protein. Due to alternative splicing events, two RINZF isoforms exist. In addition, RINZF may be phosphorylated by ATR or ATM upon DNA damage. |
Concentration |
1.7 mg/mL |
Storage |
Store at -20C. Avoid freeze / thaw cycles. |
Immunogen |
Synthetic peptide of human ZBTB10 |
Buffer |
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4 |
Purification Method |
Antigen affinity purification |
Dilution |
WB 1:500-1:2000, IHC 1:50-1:300, ELISA 1:5000-1:10000 |
Conjugation |
Unconjugated |
Calculated MW |
95 kDa |
Observed MW |
Refer to figures |
Gene Accession |
NP001099009 |
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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.