Item no. |
E-AB-18573-60 |
Manufacturer |
Elabscience
|
Amount |
60uL |
Category |
|
Type |
Antibody Polyclonal |
Applications |
IHC, ELISA |
Specific against |
Human |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
ANAPHYLATOXIN RECEPTOR, C5a anaphylatoxin chemotactic receptor, C5a anaphylatoxin receptor, C5A, C5a ligand, C5a-R, C5aR, C5AR, c5ar1, C5R1, CD88, CD88 antigen, Complement component 5 receptor 1, Complement component 5 receptor 2, Complement component 5a |
Similar products |
C5R1, C5A, C5AR, CD88, C5a anaphylatoxin receptor, C5a ligand, ANAPHYLATOXIN RECEPTOR, C5a anaphylatoxin chemotactic receptor, C5a-R, C5aR, c5ar1, CD88 antigen, Complement component 5 receptor 1, Complement component 5 receptor 1, Complement component 5 receptor 2, Complement component 5a receptor 1 |
Available |
|
Research Areas |
Cancer, Metabolism, Immunology, Signal Transduction |
Synonyms |
ANAPHYLATOXIN RECEPTOR, C5a anaphylatoxin chemotactic receptor, C5a anaphylatoxin receptor, C5A, C5a ligand, C5a-R, C5aR, C5AR, c5ar1, C5R1, CD88, CD88 antigen, Complement component 5 receptor 1, Complement component 5 receptor 2, Complement component 5a receptor 1 |
Swissprot |
P21730 |
Background |
Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a (PubMed:1847994, PubMed:8182049, PubMed:7622471, PubMed:9553099, PubMed:10636859, PubMed:15153520). The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events (PubMed:8182049, PubMed:7622471, PubMed:9553099). Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production (PubMed:10636859, PubMed:15153520). |
Concentration |
0.7 mg/mL |
Storage |
Store at -20C. Avoid freeze / thaw cycles. |
Immunogen |
Fusion protein of human C5AR1 |
Buffer |
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4 |
Purification Method |
Antigen affinity purification |
Dilution |
IHC 1:40-1:200, ELISA 1:5000-1:10000 |
Conjugation |
Unconjugated |
Gene Accession |
BC008982 |
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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.