Item no. |
E-AB-18293-120 |
Manufacturer |
Elabscience
|
Amount |
120uL |
Category |
|
Type |
Antibody Polyclonal |
Applications |
WB, ELISA |
Specific against |
Human |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
GTF2D, GTF2D1, HDL4, SCA17, TATA binding factor, TATA box binding protein, TATA box factor, TATA sequence binding protein, TATA sequence-binding protein, TATA-binding factor, TATA-box factor, TATA-box-binding protein, TBP, TBP, TFIID, Transcription initia |
Similar products |
TBP, TFIID, GTF2D, GTF2D1, SCA17, TATA binding factor, TATA box factor, TATA sequence binding protein, Transcription initiation factor TFIID TBP subunit, TATA binding factor, TATA box binding protein, TATA box factor, TATA sequence binding protein, Transcription initiation factor TFIID TBP subunit, TATA sequence-binding protein, TATA-binding factor, TATA-box factor, TATA-box-binding protein, HDL4 |
Available |
|
Research Areas |
Cancer, Epigenetics and Nuclear Signaling |
Synonyms |
GTF2D, GTF2D1, HDL4, SCA17, TATA binding factor, TATA box binding protein, TATA box factor, TATA sequence binding protein, TATA sequence-binding protein, TATA-binding factor, TATA-box factor, TATA-box-binding protein, TBP, TBP, TFIID, Transcription initiation factor TFIID TBP subunit |
Swissprot |
P20226 |
Background |
The TATA binding protein (TBP) is a transcription factor that binds specifically to a DNA sequence TATA box. This DNA sequence is found about 25-30 base pairs upstream of the transcription start site in some eukaryotic gene promoters. TBP, along with a variety of TBP-associated factors, make up the TFIID, a general transcription factor that in turn makes up part of the RNA polymerase II preinitiation complex. As one of the few proteins in the preinitation complex that binds DNA in a sequence-specific manner, it helps position RNA polymerase II over the transcription start site of the gene. However, it is estimated that only 10-20% of human promoters have TATA boxes. Therefore, TBP is probably not the only protein involved in positioning RNA polymerase II. This antibody detects human TBP (ca.40 kDa) and mouse/rat Tbp (ca.35 kDa). |
Concentration |
0.8 mg/mL |
Storage |
Store at -20C. Avoid freeze / thaw cycles. |
Immunogen |
Full length fusion protein |
Buffer |
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4 |
Purification Method |
Antigen affinity purification |
Dilution |
WB 1:500-1:2000, ELISA 1:5000-1:10000 |
Conjugation |
Unconjugated |
Calculated MW |
38 kDa |
Observed MW |
Refer to figures |
Gene Accession |
BC109054 |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.